Cargando…

Genetic and molecular features of seizure-freedom following surgical resections for focal epilepsy: A pilot study

OBJECTIVE: Seizure outcomes after brain surgery for drug-resistant epilepsy (DRE) are very heterogeneous and difficult to predict with models utilizing the current clinical, imaging, and electrophysiological variables. In this pilot study, we investigated whether genetic and molecular biomarkers (e....

Descripción completa

Detalles Bibliográficos
Autores principales:	Louis, Shreya, Busch, Robyn M., Lal, Dennis, Hockings, Jennifer, Hogue, Olivia, Morita-Sherman, Marcia, Vegh, Deborah, Najm, Imad, Ghosh, Chaitali, Bazeley, Peter, Eng, Charis, Jehi, Lara, Rotroff, Daniel M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524264/ https://www.ncbi.nlm.nih.gov/pubmed/36188379 http://dx.doi.org/10.3389/fneur.2022.942643

Ejemplares similares

Molecular subtypes of epilepsy associated with post-surgical seizure recurrence
por: Hershberger, Courtney E, et al.
Publicado: (2023)

Quantitative analysis of visually reviewed normal scalp EEG predicts seizure freedom following anterior temporal lobectomy
por: Varatharajah, Yogatheesan, et al.
Publicado: (2022)

Preliminary report: Late seizure recurrence years after epilepsy surgery may be associated with alterations in brain tissue transcriptome
por: Jehi, Lara, et al.
Publicado: (2018)

Beyond seizure freedom: Dissecting long‐term seizure control after surgical resection for drug‐resistant epilepsy
por: Hsieh, Jason K., et al.
Publicado: (2022)

Neurological disorder-associated genetic variants in individuals with psychogenic nonepileptic seizures
por: Leu, Costin, et al.
Publicado: (2020)

Sustained seizure freedom with adjunctive brivaracetam in patients with focal onset seizures
por: Lattanzi, Simona, et al.
Publicado: (2022)

Incidence and prevalence of major epilepsy-associated brain lesions
por: López-Rivera, Javier A., et al.
Publicado: (2022)

Seizure freedom following surgery for multi-focal epilepsy due to cerebral malaria
por: Piromruen, Peraya, et al.
Publicado: (2017)

Polygenic burden in focal and generalized epilepsies
por: Leu, Costin, et al.
Publicado: (2019)

Atlas of lesion locations and postsurgical seizure freedom in focal cortical dysplasia: A MELD study
por: Wagstyl, Konrad, et al.
Publicado: (2021)

Incorporation of quantitative MRI in a model to predict temporal lobe epilepsy surgery outcome
por: Morita-Sherman, Marcia, et al.
Publicado: (2021)

Molecular and subregion mechanisms of episodic memory phenotypes in temporal lobe epilepsy
por: Busch, Robyn M, et al.
Publicado: (2022)

Multimodal approach leads to seizure-freedom in a case of highly refractory drug-resistant focal epilepsy
por: Smith, Kelsey M., et al.
Publicado: (2022)

The delta between postoperative seizure freedom and persistence: Automatically detected focal slow waves after epilepsy surgery
por: Schönherr, Margit, et al.
Publicado: (2016)

Brain single cell transcriptomic profiles in episodic memory phenotypes associated with temporal lobe epilepsy
por: Busch, Robyn M., et al.
Publicado: (2022)

Integrating somatic CNV and gene expression in breast cancers from women with PTEN hamartoma tumor syndrome
por: Brewer, Takae, et al.
Publicado: (2023)

Experience of perampanel monotherapy beyond initial titration to achieve seizure freedom in patients with focal‐onset seizures with newly diagnosed or currently untreated recurrent epilepsy: A post hoc analysis of the open‐label Study 342 (FREEDOM)
por: Husni, Ryan Edbert, et al.
Publicado: (2021)

Neurobehavioral phenotype of autism spectrum disorder associated with germline heterozygous mutations in PTEN
por: Busch, Robyn M., et al.
Publicado: (2019)

Multimodal prognostic features of seizure freedom in epilepsy surgery
por: Alim-Marvasti, Ali, et al.
Publicado: (2022)

Predictors of Seizure Freedom in Pediatric Low-Grade Gliomas
por: Budnick, Hailey C, et al.
Publicado: (2022)

Continuous electroencephalography characteristics and acute symptomatic seizures in COVID-19 patients
por: Louis, Shreya, et al.
Publicado: (2020)

Effect of radiotherapy on freedom from seizures in dogs with brain tumors
por: Monforte Monteiro, Susana R., et al.
Publicado: (2020)

Neurocognitive Outcome and Seizure Freedom After Awake Surgery of Gliomas
por: Reitz, Sarah Christina, et al.
Publicado: (2022)

Longitudinal neurobehavioral profiles in children and young adults with PTEN hamartoma tumor syndrome and reliable methods for assessing neurobehavioral change
por: Busch, Robyn M., et al.
Publicado: (2023)

Unusual seizure evolution: Focal-general-focal-general
por: Smelick, Christopher, et al.
Publicado: (2018)

Rates and Predictors of Seizure Freedom With Vagus Nerve Stimulation for Intractable Epilepsy
por: Englot, Dario J., et al.
Publicado: (2015)

Resection of piriform cortex predicts seizure freedom in temporal lobe epilepsy
por: Borger, Valeri, et al.
Publicado: (2020)

Progress Toward Obtaining Seizure Freedom With New Medications in Older Adults
por: Birnbaum, Angela
Publicado: (2021)

Novel noninvasive identification of patient‐specific epileptic networks in focal epilepsies: Linking single‐photon emission computed tomography perfusion during seizures with resting‐state magnetoencephalography dynamics
por: Krishnan, Balu, et al.
Publicado: (2022)

Computational modelling of micro-seizures and focal seizure onset
por: Wang, Yujiang, et al.
Publicado: (2013)

Arousal and Consciousness in Focal Seizures
por: Blumenfeld, Hal
Publicado: (2021)

Removal of Interictal MEG-Derived Network Hubs Is Associated With Postoperative Seizure Freedom
por: Ramaraju, Sriharsha, et al.
Publicado: (2020)

Freedom From Seizures Might Be Key to Continuing Occupation After Epilepsy Surgery
por: Nozaki, Toshiki, et al.
Publicado: (2021)

What Matters to You? Looking Beyond Seizure Freedom Following Epilepsy Surgery
por: Bermeo-Ovalle, Adriana
Publicado: (2021)

High frequency oscillations in relation to interictal spikes in predicting postsurgical seizure freedom
por: Gerstl, Jakob V. E., et al.
Publicado: (2023)

Focal Seizures Cruise the Callosal Highway
por: Stafstrom, Carl E.
Publicado: (2022)

Focal non-motor seizures and subsequent focal motor seizures as the main clinical expression of GLUT-1 deficiency
por: Santarone, M.E., et al.
Publicado: (2022)

Cytochrome P450-mediated antiseizure medication interactions influence apoptosis, modulate the brain BAX/Bcl-X(L) ratio and aggravate mitochondrial stressors in human pharmacoresistant epilepsy
por: Ghosh, Chaitali, et al.
Publicado: (2022)

Intracranial monitoring contributes to seizure freedom for temporal lobectomy patients with nonconcordant preoperative data
por: Sokolov, Elisaveta, et al.
Publicado: (2021)

Post-Operative Seizure Freedom Need not be Elusive in Mild Oligodendroglial Hyperplasia and Epilepsy (MOGHE)
por: Chatterjee, Aparajita, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_l4p4l8ertbiqlf6mqpgksovijf