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Neurologic sequelae of phosphide poisoning: A case report

BACKGROUND: Aluminum phosphide (ALP) is extremely toxic with a high mortality rate, mainly due to its cardiovascular complications. Some neurologic effects have also been reported with this pesticide. CASE PRESENTATION: We present a 23-year-old male who presented with confusion after ingestion of a...

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Autores principales: Shafiee Dolat Abadi, Sahel, Zamani, Nasim, Abbasi, Sahar, Shojaei, Maziar, Hassanian-Moghaddam, Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524356/
https://www.ncbi.nlm.nih.gov/pubmed/36188402
http://dx.doi.org/10.3389/fneur.2022.888493
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author Shafiee Dolat Abadi, Sahel
Zamani, Nasim
Abbasi, Sahar
Shojaei, Maziar
Hassanian-Moghaddam, Hossein
author_facet Shafiee Dolat Abadi, Sahel
Zamani, Nasim
Abbasi, Sahar
Shojaei, Maziar
Hassanian-Moghaddam, Hossein
author_sort Shafiee Dolat Abadi, Sahel
collection PubMed
description BACKGROUND: Aluminum phosphide (ALP) is extremely toxic with a high mortality rate, mainly due to its cardiovascular complications. Some neurologic effects have also been reported with this pesticide. CASE PRESENTATION: We present a 23-year-old male who presented with confusion after ingestion of a toxic dose of ALP. Computerized tomography scan demonstrated diffuse bilateral hypoattenuation of the cerebellar hemispheres, midbrain, thalamus, and globus pallidus resulting in tonsillar and transtentorial herniation and eventually brain death four days after admission. CONCLUSIONS: This is the first documented case of neurologic sequela following phosphide poisoning that emphasizes the importance of brain imaging studies for patients with loss of consciousness.
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spelling pubmed-95243562022-10-01 Neurologic sequelae of phosphide poisoning: A case report Shafiee Dolat Abadi, Sahel Zamani, Nasim Abbasi, Sahar Shojaei, Maziar Hassanian-Moghaddam, Hossein Front Neurol Neurology BACKGROUND: Aluminum phosphide (ALP) is extremely toxic with a high mortality rate, mainly due to its cardiovascular complications. Some neurologic effects have also been reported with this pesticide. CASE PRESENTATION: We present a 23-year-old male who presented with confusion after ingestion of a toxic dose of ALP. Computerized tomography scan demonstrated diffuse bilateral hypoattenuation of the cerebellar hemispheres, midbrain, thalamus, and globus pallidus resulting in tonsillar and transtentorial herniation and eventually brain death four days after admission. CONCLUSIONS: This is the first documented case of neurologic sequela following phosphide poisoning that emphasizes the importance of brain imaging studies for patients with loss of consciousness. Frontiers Media S.A. 2022-09-16 /pmc/articles/PMC9524356/ /pubmed/36188402 http://dx.doi.org/10.3389/fneur.2022.888493 Text en Copyright © 2022 Shafiee Dolat Abadi, Zamani, Abbasi, Shojaei and Hassanian-Moghaddam. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Shafiee Dolat Abadi, Sahel
Zamani, Nasim
Abbasi, Sahar
Shojaei, Maziar
Hassanian-Moghaddam, Hossein
Neurologic sequelae of phosphide poisoning: A case report
title Neurologic sequelae of phosphide poisoning: A case report
title_full Neurologic sequelae of phosphide poisoning: A case report
title_fullStr Neurologic sequelae of phosphide poisoning: A case report
title_full_unstemmed Neurologic sequelae of phosphide poisoning: A case report
title_short Neurologic sequelae of phosphide poisoning: A case report
title_sort neurologic sequelae of phosphide poisoning: a case report
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524356/
https://www.ncbi.nlm.nih.gov/pubmed/36188402
http://dx.doi.org/10.3389/fneur.2022.888493
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