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Neurologic sequelae of phosphide poisoning: A case report
BACKGROUND: Aluminum phosphide (ALP) is extremely toxic with a high mortality rate, mainly due to its cardiovascular complications. Some neurologic effects have also been reported with this pesticide. CASE PRESENTATION: We present a 23-year-old male who presented with confusion after ingestion of a...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524356/ https://www.ncbi.nlm.nih.gov/pubmed/36188402 http://dx.doi.org/10.3389/fneur.2022.888493 |
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author | Shafiee Dolat Abadi, Sahel Zamani, Nasim Abbasi, Sahar Shojaei, Maziar Hassanian-Moghaddam, Hossein |
author_facet | Shafiee Dolat Abadi, Sahel Zamani, Nasim Abbasi, Sahar Shojaei, Maziar Hassanian-Moghaddam, Hossein |
author_sort | Shafiee Dolat Abadi, Sahel |
collection | PubMed |
description | BACKGROUND: Aluminum phosphide (ALP) is extremely toxic with a high mortality rate, mainly due to its cardiovascular complications. Some neurologic effects have also been reported with this pesticide. CASE PRESENTATION: We present a 23-year-old male who presented with confusion after ingestion of a toxic dose of ALP. Computerized tomography scan demonstrated diffuse bilateral hypoattenuation of the cerebellar hemispheres, midbrain, thalamus, and globus pallidus resulting in tonsillar and transtentorial herniation and eventually brain death four days after admission. CONCLUSIONS: This is the first documented case of neurologic sequela following phosphide poisoning that emphasizes the importance of brain imaging studies for patients with loss of consciousness. |
format | Online Article Text |
id | pubmed-9524356 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-95243562022-10-01 Neurologic sequelae of phosphide poisoning: A case report Shafiee Dolat Abadi, Sahel Zamani, Nasim Abbasi, Sahar Shojaei, Maziar Hassanian-Moghaddam, Hossein Front Neurol Neurology BACKGROUND: Aluminum phosphide (ALP) is extremely toxic with a high mortality rate, mainly due to its cardiovascular complications. Some neurologic effects have also been reported with this pesticide. CASE PRESENTATION: We present a 23-year-old male who presented with confusion after ingestion of a toxic dose of ALP. Computerized tomography scan demonstrated diffuse bilateral hypoattenuation of the cerebellar hemispheres, midbrain, thalamus, and globus pallidus resulting in tonsillar and transtentorial herniation and eventually brain death four days after admission. CONCLUSIONS: This is the first documented case of neurologic sequela following phosphide poisoning that emphasizes the importance of brain imaging studies for patients with loss of consciousness. Frontiers Media S.A. 2022-09-16 /pmc/articles/PMC9524356/ /pubmed/36188402 http://dx.doi.org/10.3389/fneur.2022.888493 Text en Copyright © 2022 Shafiee Dolat Abadi, Zamani, Abbasi, Shojaei and Hassanian-Moghaddam. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neurology Shafiee Dolat Abadi, Sahel Zamani, Nasim Abbasi, Sahar Shojaei, Maziar Hassanian-Moghaddam, Hossein Neurologic sequelae of phosphide poisoning: A case report |
title | Neurologic sequelae of phosphide poisoning: A case report |
title_full | Neurologic sequelae of phosphide poisoning: A case report |
title_fullStr | Neurologic sequelae of phosphide poisoning: A case report |
title_full_unstemmed | Neurologic sequelae of phosphide poisoning: A case report |
title_short | Neurologic sequelae of phosphide poisoning: A case report |
title_sort | neurologic sequelae of phosphide poisoning: a case report |
topic | Neurology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524356/ https://www.ncbi.nlm.nih.gov/pubmed/36188402 http://dx.doi.org/10.3389/fneur.2022.888493 |
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