Amyloid Beta Is Internalized via Macropinocytosis, an HSPG- and Lipid Raft-Dependent and Rac1-Mediated Process

Intracellular amyloid β peptide (Aβ) accumulation has drawn attention in relation to the pathophysiology of Alzheimer’s disease in addition to its extracellular deposition as senile plaque. Cellular uptake of extracellular Aβ is one of the possible mechanisms by which intracellular Aβ deposits form....

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Detalles Bibliográficos
Autores principales: Nazere, Keyoumu, Takahashi, Tetsuya, Hara, Naoyuki, Muguruma, Kazuki, Nakamori, Masahiro, Yamazaki, Yu, Morino, Hiroyuki, Maruyama, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524458/
https://www.ncbi.nlm.nih.gov/pubmed/36187354
http://dx.doi.org/10.3389/fnmol.2022.804702

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524458/
https://www.ncbi.nlm.nih.gov/pubmed/36187354
http://dx.doi.org/10.3389/fnmol.2022.804702

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