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Characterizing Absorption Properties of Dispersible Pretomanid Tablets Using Population Pharmacokinetic Modelling

BACKGROUND AND INTRODUCTION: The dispersible tablet formulation (DTF) of pretomanid has been developed to facilitate future use in children. This work aimed to assess the pharmacokinetics (PK) and relative bioavailability of the DTF compared to the marketed formulation (MF) and the potential influen...

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Detalles Bibliográficos
Autores principales: Zou, Yuanxi, Nedelman, Jerry, Lombardi, Antonio, Pappas, Frances, Karlsson, Mats O., Svensson, Elin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524735/
https://www.ncbi.nlm.nih.gov/pubmed/36180816
http://dx.doi.org/10.1007/s40262-022-01163-w