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Regulation of cGAS-STING Pathway - Implications for Systemic Lupus Erythematosus

Type I interferon (IFN-I) is implicated in the pathogenesis of systemic lupus erythematosus (SLE) and the closely associated monogenic autoinflammatory disorders termed the “interferonopathies.” Recently, the cytosolic DNA sensor cyclic guanosine monophosphate-adenosine monophosphate synthase (cGAS)...

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Detalles Bibliográficos
Autores principales:	Hagiwara, Audrey M., Moore, Richard E., Wallace, Daniel J., Ishimori, Mariko, Jefferies, Caroline A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Sciendo 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524788/ https://www.ncbi.nlm.nih.gov/pubmed/36465073 http://dx.doi.org/10.2478/rir-2021-0023

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