Ca(2+) channels couple spiking to mitochondrial metabolism in substantia nigra dopaminergic neurons

How do neurons match generation of adenosine triphosphate by mitochondria to the bioenergetic demands of regenerative activity? Although the subject of speculation, this coupling is still poorly understood, particularly in neurons that are tonically active. To help fill this gap, pacemaking substant...

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Detalles Bibliográficos
Autores principales: Zampese, Enrico, Wokosin, David L., Gonzalez-Rodriguez, Patricia, Guzman, Jaime N., Tkatch, Tatiana, Kondapalli, Jyothisri, Surmeier, William C., D’Alessandro, Karis B., De Stefani, Diego, Rizzuto, Rosario, Iino, Masamitsu, Molkentin, Jeffery D., Chandel, Navdeep S., Schumacker, Paul T., Surmeier, D. James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524841/
https://www.ncbi.nlm.nih.gov/pubmed/36179023
http://dx.doi.org/10.1126/sciadv.abp8701

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