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Peritumoral tertiary lymphoid structure and tumor stroma percentage predict the prognosis of patients with non-metastatic colorectal cancer

BACKGROUND: Tertiary lymphoid structures (TLSs) are crucial in promoting and maintaining positive anti-tumor immune responses. The tumor stroma has a powerful immunosuppressive function that could exclude tumor-infiltrating lymphocytes from the tumor beds and lead to a “cold” phenotype. TLSs and tum...

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Detalles Bibliográficos
Autores principales: Wang, Qianyu, Shen, Xiaofei, An, Ran, Bai, Junchao, Dong, Junhua, Cai, Huiyun, Zhu, Hongyan, Zhong, Wentao, Chen, Wenliang, Liu, Aijun, Du, Junfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524924/
https://www.ncbi.nlm.nih.gov/pubmed/36189233
http://dx.doi.org/10.3389/fimmu.2022.962056