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Prediction of gene co-expression from chromatin contacts with graph attention network

MOTIVATION: The technology of high-throughput chromatin conformation capture (Hi-C) allows genome-wide measurement of chromatin interactions. Several studies have shown statistically significant relationships between gene–gene spatial contacts and their co-expression. It is desirable to uncover epig...

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Detalles Bibliográficos
Autores principales: Zhang, Ke, Wang, Chenxi, Sun, Liping, Zheng, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525008/
https://www.ncbi.nlm.nih.gov/pubmed/35929807
http://dx.doi.org/10.1093/bioinformatics/btac535

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