Repressor element 1-silencing transcription factor deficiency yields profound hearing loss through K(v)7.4 channel upsurge in auditory neurons and hair cells

Repressor element 1-silencing transcription factor (REST) is a transcriptional repressor that recognizes neuron-restrictive silencer elements in the mammalian genomes in a tissue- and cell-specific manner. The identity of REST target genes and molecular details of how REST regulates them are emergin...

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Detalles Bibliográficos
Autores principales: Zhang, Haiwei, Li, Hongchen, Lu, Mingshun, Wang, Shengnan, Ma, Xueya, Wang, Fei, Liu, Jiaxi, Li, Xinyu, Yang, Haichao, Zhang, Fan, Shen, Haitao, Buckley, Noel J, Gamper, Nikita, Yamoah, Ebenezer N, Lv, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525063/
https://www.ncbi.nlm.nih.gov/pubmed/36125121
http://dx.doi.org/10.7554/eLife.76754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525063/
https://www.ncbi.nlm.nih.gov/pubmed/36125121
http://dx.doi.org/10.7554/eLife.76754

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