Efficacy, Safety, Pharmacokinetics, and Microbiome Changes of Ibezapolstat in Adults with Clostridioides difficile Infection: A Phase 2a Multicenter Clinical Trial( )

BACKGROUND: This study was the first human validation of the gram-positive bacterial DNA polymerase IIIC target in patients with Clostridioides difficile infection. The primary objectives were to assess clinical cure rates and adverse events (AEs). Secondary objectives were to evaluate plasma/fecal...

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Detalles Bibliográficos
Autores principales: Garey, Kevin W, McPherson, Jacob, Dinh, An Q, Hu, Chenlin, Jo, Jinhee, Wang, Weiqun, Lancaster, Chris K, Gonzales-Luna, Anne J, Loveall, Caroline, Begum, Khurshida, Jahangir Alam, M, Silverman, Michael H, Hanson, Blake M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Major Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525077/
https://www.ncbi.nlm.nih.gov/pubmed/35134880
http://dx.doi.org/10.1093/cid/ciac096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525077/
https://www.ncbi.nlm.nih.gov/pubmed/35134880
http://dx.doi.org/10.1093/cid/ciac096

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