Impact of feminizing hormone therapy on tenofovir and emtricitabine plasma pharmacokinetics: a nested drug–drug interaction study in a cohort of Brazilian transgender women using HIV pre-exposure prophylaxis

OBJECTIVES: Potential interactions between feminizing hormone therapy (FHT) and pre-exposure prophylaxis (PrEP) may be a barrier to PrEP use among transgender women (TGW). We aimed to assess the impact of FHT on PrEP plasma pharmacokinetics (PK) among TGW. METHODS: This was a PK substudy of the effe...

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Detalles Bibliográficos
Autores principales: Cattani, Vitória Berg, Jalil, Emilia Moreira, Eksterman, Leonardo, Torres, Thiago, Cardoso, Sandra Wagner, Castro, Cristiane R V, Monteiro, Laylla, Wilson, Erin, Bushman, Lane, Anderson, Peter, Veloso, Valdilea Gonçalves, Grinsztejn, Beatriz, Estrela, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525093/
https://www.ncbi.nlm.nih.gov/pubmed/35815666
http://dx.doi.org/10.1093/jac/dkac229

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