Cargando…

The pharmacology, pharmacokinetics, and toxicity of spinosin: A mini review

Spinosin, a natural flavone-C-glycoside that is mainly isolated from the seeds of Ziziphus jujuba Mill. var. spinosa. It exerts the effects to ameliorate the neurological disorders, such as hypnosis effects, improvement of cognitive function, sedation effects, and anxiolytic effects, as well as anti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kuang, Xiaolan, She, Ganshu, Ma, Ting, Cai, Wanna, Zhao, Jingjing, Liu, Bo, Xu, Fangfang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525219/ https://www.ncbi.nlm.nih.gov/pubmed/36193419 http://dx.doi.org/10.3389/fphar.2022.938395

Ejemplares similares

Oridonin: A Review of Its Pharmacology, Pharmacokinetics and Toxicity
por: Li, Xiang, et al.
Publicado: (2021)

Jatrorrhizine: A Review of Sources, Pharmacology, Pharmacokinetics and Toxicity
por: Zhong, Furong, et al.
Publicado: (2022)

Quantitative and pattern recognition analyses of magnoflorine, spinosin, 6′′′-feruloyl spinosin and jujuboside A by HPLC in Zizyphi Semen
por: Kim, Won Il, et al.
Publicado: (2013)

New spinosin derivatives from the seeds of Ziziphus mauritiana
por: Wang, Bin, et al.
Publicado: (2013)

Sinapis Semen: A review on phytochemistry, pharmacology, toxicity, analytical methods and pharmacokinetics
por: Dang, Rui, et al.
Publicado: (2023)

The Traditional Uses, Phytochemistry, Pharmacokinetics, Pharmacology, Toxicity, and Applications of Corydalis saxicola Bunting: A Review
por: Guo, Yanru, et al.
Publicado: (2022)

Pharmacology, Toxicity, Bioavailability, and Formulation of Magnolol: An Update
por: Lin, Yiping, et al.
Publicado: (2021)

Pharmacological Activity, Pharmacokinetics, and Toxicity of Timosaponin AIII, a Natural Product Isolated From Anemarrhena asphodeloides Bunge: A Review
por: Lin, Yan, et al.
Publicado: (2020)

Acori Tatarinowii Rhizoma: A comprehensive review of its chemical composition, pharmacology, pharmacokinetics and toxicity
por: Wen, Jianxia, et al.
Publicado: (2023)

The transport mechanism of monocarboxylate transporter on spinosin in Caco-2 cells
por: Meng, Xiang Le, et al.
Publicado: (2016)

Tripterygium hypoglaucum (Lévl.) Hutch and Its Main Bioactive Components: Recent Advances in Pharmacological Activity, Pharmacokinetics and Potential Toxicity
por: Zhao, Junqi, et al.
Publicado: (2021)

A Review of Pharmacology, Toxicity and Pharmacokinetics of 2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-Glucoside
por: Wang, Cheng, et al.
Publicado: (2022)

Alpinetin: A Review of Its Pharmacology and Pharmacokinetics
por: Zhao, Ge, et al.
Publicado: (2022)

A Systematic Review of the Pharmacology, Toxicology and Pharmacokinetics of Matrine
por: You, Longtai, et al.
Publicado: (2020)

Constituents, Pharmacokinetics, and Pharmacology of Gegen-Qinlian Decoction
por: Lu, Jing-Ze, et al.
Publicado: (2021)

Spinosin Attenuates Alzheimer’s Disease-Associated Synaptic Dysfunction via Regulation of Plasmin Activity
por: Cai, Mudan, et al.
Publicado: (2020)

Preclinical and Clinical Pharmacology of Hydrocodone for Chronic Pain: A Mini Review
por: Cardia, Luigi, et al.
Publicado: (2018)

Neuroprotective Effects of Spinosin on Recovery of Learning and Memory in a Mouse Model of Alzheimer’s Disease
por: Xu, Fanxing, et al.
Publicado: (2019)

Spinosin ameliorates insulin resistance by suppressing reactive oxygen species-associated inflammation
por: Ge, Chi-yu, et al.
Publicado: (2022)

Spinosin and 6‴-Feruloylspinosin protect the heart against acute myocardial ischemia and reperfusion in rats
por: Gu, Minhua, et al.
Publicado: (2019)

Monotropein: A comprehensive review of biosynthesis, physicochemical properties, pharmacokinetics, and pharmacology
por: Wu, Mingquan, et al.
Publicado: (2023)

Spinosin Inhibits Aβ(1-42) Production and Aggregation via Activating Nrf2/HO-1 Pathway
por: Zhang, Xiaoying, et al.
Publicado: (2020)

A review of the botany, ethnopharmacology, phytochemistry, analysis method and quality control, processing methods, pharmacological effects, pharmacokinetics and toxicity of codonopsis radix
por: Dong, Jiaojiao, et al.
Publicado: (2023)

A Review of the Ethnopharmacology, Phytochemistry, Pharmacology, Application, Quality Control, Processing, Toxicology, and Pharmacokinetics of the Dried Rhizome of Atractylodes macrocephala
por: Yang, Liu, et al.
Publicado: (2021)

The pharmacokinetics profiles, pharmacological properties, and toxicological risks of dehydroevodiamine: A review
por: Fu, Shubin, et al.
Publicado: (2022)

Biotransformation, Pharmacokinetics, and Pharmacological Activities of Ginsenoside Rd Against Multiple Diseases
por: Li, Jing, et al.
Publicado: (2022)

Pharmacology, toxicity and pharmacokinetics of acetylshikonin: a review
por: Zhang, Zhiqin, et al.
Publicado: (2020)

Advances in Chemical Constituents, Clinical Applications, Pharmacology, Pharmacokinetics and Toxicology of Erigeron breviscapus
por: Wu, Ruixia, et al.
Publicado: (2021)

Hydroxysafflor Yellow A: A Systematical Review on Botanical Resources, Physicochemical Properties, Drug Delivery System, Pharmacokinetics, and Pharmacological Effects
por: Zhao, Feng, et al.
Publicado: (2020)

Identification of Pharmacokinetic Markers for Guanxin Danshen Drop Pills in Rats by Combination of Pharmacokinetics, Systems Pharmacology, and Pharmacodynamic Assays
por: Yao, Hong, et al.
Publicado: (2018)

Traditional Chinese Medicine of Angelicae Pubescentis Radix: A Review of Phytochemistry, Pharmacology and Pharmacokinetics
por: Lu, Yaqi, et al.
Publicado: (2020)

Properties, Pharmacology, and Pharmacokinetics of Active Indole and Oxindole Alkaloids in Uncaria Hook
por: Kushida, Hirotaka, et al.
Publicado: (2021)

Limonin: A Review of Its Pharmacology, Toxicity, and Pharmacokinetics
por: Fan, Shunming, et al.
Publicado: (2019)

Identification of pharmacokinetic markers for safflower injection using a combination of system pharmacology, multicomponent pharmacokinetics, and quantitative proteomics study
por: Shi, Peiying, et al.
Publicado: (2022)

An Integrated Pharmacokinetic Study of an Acanthopanax senticosus Extract Preparation by Combination of Virtual Screening, Systems Pharmacology, and Multi-Component Pharmacokinetics in Rats
por: Shi, Peiying, et al.
Publicado: (2020)

Tubeimoside-1: A review of its antitumor effects, pharmacokinetics, toxicity, and targeting preparations
por: Wang, Chang-Lin, et al.
Publicado: (2022)

Pharmacodynamics, Network Pharmacology, and Pharmacokinetics of Chinese Medicine Formula 9002A in the Treatment of Alzheimer’s Disease
por: Tang, Chunlan, et al.
Publicado: (2022)

Sinensetin: An Insight on Its Pharmacological Activities, Mechanisms of Action and Toxicity
por: Han Jie, Lee, et al.
Publicado: (2021)

A Comprehensive Review on the Chemical Properties, Plant Sources, Pharmacological Activities, Pharmacokinetic and Toxicological Characteristics of Tetrahydropalmatine
por: Du, Qinyun, et al.
Publicado: (2022)

Mercury and Mercury-Containing Preparations: History of Use, Clinical Applications, Pharmacology, Toxicology, and Pharmacokinetics in Traditional Chinese Medicine
por: Zhao, Meiling, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_lk248e98qu361tv0h2d468mbvp