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ANGEL2 phosphatase activity is required for non-canonical mitochondrial RNA processing
Canonical RNA processing in mammalian mitochondria is defined by tRNAs acting as recognition sites for nucleases to release flanking transcripts. The relevant factors, their structures, and mechanism are well described, but not all mitochondrial transcripts are punctuated by tRNAs, and their mode of...
Autores principales: | Clemente, Paula, Calvo-Garrido, Javier, Pearce, Sarah F., Schober, Florian A., Shigematsu, Megumi, Siira, Stefan J., Laine, Isabelle, Spåhr, Henrik, Steinmetzger, Christian, Petzold, Katja, Kirino, Yohei, Wibom, Rolf, Rackham, Oliver, Filipovska, Aleksandra, Rorbach, Joanna, Freyer, Christoph, Wredenberg, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525292/ https://www.ncbi.nlm.nih.gov/pubmed/36180430 http://dx.doi.org/10.1038/s41467-022-33368-9 |
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