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Extreme conditions affect neuronal oscillations of cerebral cortices in humans in the China Space Station and on Earth

Rhythmical oscillations of neural populations can reflect working memory performance. However, whether neuronal oscillations of the cerebral cortex change in extreme environments, especially in a space station, remains unclear. Here, we recorded electroencephalography (EEG) signals when volunteers a...

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Autores principales: Zhang, Peng, Yan, Juan, Liu, Zhongqi, Yu, Hongqiang, Zhao, Rui, Zhou, Qianxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525319/
https://www.ncbi.nlm.nih.gov/pubmed/36180522
http://dx.doi.org/10.1038/s42003-022-04018-z
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author Zhang, Peng
Yan, Juan
Liu, Zhongqi
Yu, Hongqiang
Zhao, Rui
Zhou, Qianxiang
author_facet Zhang, Peng
Yan, Juan
Liu, Zhongqi
Yu, Hongqiang
Zhao, Rui
Zhou, Qianxiang
author_sort Zhang, Peng
collection PubMed
description Rhythmical oscillations of neural populations can reflect working memory performance. However, whether neuronal oscillations of the cerebral cortex change in extreme environments, especially in a space station, remains unclear. Here, we recorded electroencephalography (EEG) signals when volunteers and astronauts were executing a memory task in extreme working conditions. Our experiments showed that two extreme conditions affect neuronal oscillations of the cerebral cortex and manifest in different ways. Lengthy periods of mental work impairs the gating mechanism formed by theta-gamma phase-amplitude coupling of two cortical areas, and sleep deprivation disrupts synaptic homeostasis, as reflected by the substantial increase in theta wave activity in the cortical frontal-central area. In addition, we excluded the possibility that nutritional supply or psychological situations caused decoupled theta-gamma phase-amplitude coupling or an imbalance in theta wave activity increase. Therefore, we speculate that the decoupled theta-gamma phase-amplitude coupling detected in astronauts results from their lengthy periods of mental work in the China Space Station. Furthermore, comparing preflight and inflight experiments, we find that long-term spaceflight and other hazards in the space station could worsen this decoupling evolution. This particular neuronal oscillation mechanism in the cerebral cortex could guide countermeasures for the inadaptability of humans working in spaceflight.
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spelling pubmed-95253192022-10-02 Extreme conditions affect neuronal oscillations of cerebral cortices in humans in the China Space Station and on Earth Zhang, Peng Yan, Juan Liu, Zhongqi Yu, Hongqiang Zhao, Rui Zhou, Qianxiang Commun Biol Article Rhythmical oscillations of neural populations can reflect working memory performance. However, whether neuronal oscillations of the cerebral cortex change in extreme environments, especially in a space station, remains unclear. Here, we recorded electroencephalography (EEG) signals when volunteers and astronauts were executing a memory task in extreme working conditions. Our experiments showed that two extreme conditions affect neuronal oscillations of the cerebral cortex and manifest in different ways. Lengthy periods of mental work impairs the gating mechanism formed by theta-gamma phase-amplitude coupling of two cortical areas, and sleep deprivation disrupts synaptic homeostasis, as reflected by the substantial increase in theta wave activity in the cortical frontal-central area. In addition, we excluded the possibility that nutritional supply or psychological situations caused decoupled theta-gamma phase-amplitude coupling or an imbalance in theta wave activity increase. Therefore, we speculate that the decoupled theta-gamma phase-amplitude coupling detected in astronauts results from their lengthy periods of mental work in the China Space Station. Furthermore, comparing preflight and inflight experiments, we find that long-term spaceflight and other hazards in the space station could worsen this decoupling evolution. This particular neuronal oscillation mechanism in the cerebral cortex could guide countermeasures for the inadaptability of humans working in spaceflight. Nature Publishing Group UK 2022-09-30 /pmc/articles/PMC9525319/ /pubmed/36180522 http://dx.doi.org/10.1038/s42003-022-04018-z Text en © The Author(s) 2022, corrected publication 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Zhang, Peng
Yan, Juan
Liu, Zhongqi
Yu, Hongqiang
Zhao, Rui
Zhou, Qianxiang
Extreme conditions affect neuronal oscillations of cerebral cortices in humans in the China Space Station and on Earth
title Extreme conditions affect neuronal oscillations of cerebral cortices in humans in the China Space Station and on Earth
title_full Extreme conditions affect neuronal oscillations of cerebral cortices in humans in the China Space Station and on Earth
title_fullStr Extreme conditions affect neuronal oscillations of cerebral cortices in humans in the China Space Station and on Earth
title_full_unstemmed Extreme conditions affect neuronal oscillations of cerebral cortices in humans in the China Space Station and on Earth
title_short Extreme conditions affect neuronal oscillations of cerebral cortices in humans in the China Space Station and on Earth
title_sort extreme conditions affect neuronal oscillations of cerebral cortices in humans in the china space station and on earth
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525319/
https://www.ncbi.nlm.nih.gov/pubmed/36180522
http://dx.doi.org/10.1038/s42003-022-04018-z
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