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Bacillus clausii for Gastrointestinal Disorders: A Narrative Literature Review

The gut microbiota is intrinsically linked to human health; disturbances in microbial homeostasis are implicated in both intestinal and extraintestinal disorders. Probiotics are “live microorganisms that, when administered in adequate amounts, confer a health benefit on the host,” and many commercia...

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Autores principales: Acosta-Rodríguez-Bueno, Carlos Patricio, Abreu y Abreu, Ana Teresa, Guarner, Francisco, Guno, Mary Jean V., Pehlivanoğlu, Ender, Perez, Marcos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525334/
https://www.ncbi.nlm.nih.gov/pubmed/36018495
http://dx.doi.org/10.1007/s12325-022-02285-0
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author Acosta-Rodríguez-Bueno, Carlos Patricio
Abreu y Abreu, Ana Teresa
Guarner, Francisco
Guno, Mary Jean V.
Pehlivanoğlu, Ender
Perez, Marcos
author_facet Acosta-Rodríguez-Bueno, Carlos Patricio
Abreu y Abreu, Ana Teresa
Guarner, Francisco
Guno, Mary Jean V.
Pehlivanoğlu, Ender
Perez, Marcos
author_sort Acosta-Rodríguez-Bueno, Carlos Patricio
collection PubMed
description The gut microbiota is intrinsically linked to human health; disturbances in microbial homeostasis are implicated in both intestinal and extraintestinal disorders. Probiotics are “live microorganisms that, when administered in adequate amounts, confer a health benefit on the host,” and many commercial preparations comprising a diverse range of species are available. While probiotics have been much researched, better understanding of the probiotic effects and applications of species such as Bacillus clausii is warranted. In this narrative literature review, we review the characteristics and mechanisms of action supporting B. clausii as a probiotic and discuss the evidence from clinical studies evaluating B. clausii probiotics for the management of a variety of gastrointestinal disorders and symptoms in children and adults. Finally, we highlight the challenges of future research and the need for more robust and diverse clinical evidence to guide physicians in the clinical application of probiotics for gastrointestinal disorders and other conditions. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s12325-022-02285-0.
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spelling pubmed-95253342022-10-02 Bacillus clausii for Gastrointestinal Disorders: A Narrative Literature Review Acosta-Rodríguez-Bueno, Carlos Patricio Abreu y Abreu, Ana Teresa Guarner, Francisco Guno, Mary Jean V. Pehlivanoğlu, Ender Perez, Marcos Adv Ther Review The gut microbiota is intrinsically linked to human health; disturbances in microbial homeostasis are implicated in both intestinal and extraintestinal disorders. Probiotics are “live microorganisms that, when administered in adequate amounts, confer a health benefit on the host,” and many commercial preparations comprising a diverse range of species are available. While probiotics have been much researched, better understanding of the probiotic effects and applications of species such as Bacillus clausii is warranted. In this narrative literature review, we review the characteristics and mechanisms of action supporting B. clausii as a probiotic and discuss the evidence from clinical studies evaluating B. clausii probiotics for the management of a variety of gastrointestinal disorders and symptoms in children and adults. Finally, we highlight the challenges of future research and the need for more robust and diverse clinical evidence to guide physicians in the clinical application of probiotics for gastrointestinal disorders and other conditions. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s12325-022-02285-0. Springer Healthcare 2022-08-26 2022 /pmc/articles/PMC9525334/ /pubmed/36018495 http://dx.doi.org/10.1007/s12325-022-02285-0 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/Open AccessThis article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Review
Acosta-Rodríguez-Bueno, Carlos Patricio
Abreu y Abreu, Ana Teresa
Guarner, Francisco
Guno, Mary Jean V.
Pehlivanoğlu, Ender
Perez, Marcos
Bacillus clausii for Gastrointestinal Disorders: A Narrative Literature Review
title Bacillus clausii for Gastrointestinal Disorders: A Narrative Literature Review
title_full Bacillus clausii for Gastrointestinal Disorders: A Narrative Literature Review
title_fullStr Bacillus clausii for Gastrointestinal Disorders: A Narrative Literature Review
title_full_unstemmed Bacillus clausii for Gastrointestinal Disorders: A Narrative Literature Review
title_short Bacillus clausii for Gastrointestinal Disorders: A Narrative Literature Review
title_sort bacillus clausii for gastrointestinal disorders: a narrative literature review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525334/
https://www.ncbi.nlm.nih.gov/pubmed/36018495
http://dx.doi.org/10.1007/s12325-022-02285-0
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