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Hypoalbuminemia affects the spatio-temporal tissue distribution of ochratoxin A in liver and kidneys: consequences for organ toxicity

Hypoalbuminemia (HA) is frequently observed in systemic inflammatory diseases and in liver disease. However, the influence of HA on the pharmacokinetics and toxicity of compounds with high plasma albumin binding remained insufficiently studied. The ‘lack-of-delivery-concept’ postulates that HA leads...

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Detalles Bibliográficos
Autores principales:	Hassan, Reham, Friebel, Adrian, Brackhagen, Lisa, Hobloss, Zaynab, Myllys, Maiju, González, Daniela, Albrecht, Wiebke, Mohammed, Elsayed S. I., Seddek, Abdel-latif, Marchan, Rosemarie, Cadenas, Cristina, Cramer, Benedikt, Humpf, Hans-Ulrich, Hartl, Lukas, Simbrunner, Benedikt, Reiberger, Thomas, Trauner, Michael, Hoehme, Stefan, Degen, Gisela H., Hengstler, Jan G., Ghallab, Ahmed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2022
Materias:	Toxicokinetics and Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525345/ https://www.ncbi.nlm.nih.gov/pubmed/35962801 http://dx.doi.org/10.1007/s00204-022-03361-8

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