Cargando…
Metabolic profiling as a powerful tool for the analysis of cellular alterations caused by 20 mycotoxins in HepG2 cells
Mycotoxins are secondary fungal metabolites which exhibit toxic effects in low concentrations. Several mycotoxins are described as carcinogenic or immunosuppressive, but their underlying modes of action especially on molecular level have not yet been entirely elucidated. Metabolic profiling as part...
Autores principales: | Gerdemann, Andrea, Behrens, Matthias, Esselen, Melanie, Humpf, Hans-Ulrich |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525358/ https://www.ncbi.nlm.nih.gov/pubmed/35932296 http://dx.doi.org/10.1007/s00204-022-03348-5 |
Ejemplares similares
-
Toxicometabolomics of the new psychoactive substances α-PBP and α-PEP studied in HepaRG cell incubates by means of untargeted metabolomics revealed unexpected amino acid adducts
por: Manier, Sascha K., et al.
Publicado: (2020) -
Assessment of the impact of mitochondrial genotype upon drug-induced mitochondrial dysfunction in platelets derived from healthy volunteers
por: Ball, Amy L., et al.
Publicado: (2021) -
Transcriptional profiling of the response to the trichloroethylene metabolite S-(1,2-dichlorovinyl)-l-cysteine revealed activation of the eIF2α/ATF4 integrated stress response in two in vitro placental models
por: Elkin, Elana R., et al.
Publicado: (2021) -
Metabolomic analysis to discriminate drug-induced liver injury (DILI) phenotypes
por: Quintás, Guillermo, et al.
Publicado: (2021) -
New insights into the mechanisms underlying 5-fluorouracil-induced intestinal toxicity based on transcriptomic and metabolomic responses in human intestinal organoids
por: Rodrigues, Daniela, et al.
Publicado: (2021)