Cargando…

A first-in-human study of [(68)Ga]Ga-CDI: a positron emitting radiopharmaceutical for imaging tumour cell death

PURPOSE: This study assesses human biodistribution, radiation dosimetry, safety and tumour uptake of cell death indicator labelled with (68)Ga ([(68)Ga]Ga-CDI), a novel radiopharmaceutical that can image multiple forms of cell death. METHODS: Five participants with at least one extracranial site of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ho Shon, Ivan, Hennessy, Thomas, Guille, Jennifer, Gotsbacher, Michael P., Lay, Angelina J., McBride, Bruce, Codd, Rachel, Hogg, Philip J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525422/ https://www.ncbi.nlm.nih.gov/pubmed/35779082 http://dx.doi.org/10.1007/s00259-022-05880-z

Ejemplares similares

Prospective of (68)Ga-Radiopharmaceutical Development
por: Velikyan, Irina
Publicado: (2013)

[(68)Ga]Ga-DOTA-TOC: The First FDA-Approved (68)Ga-Radiopharmaceutical for PET Imaging
por: Hennrich, Ute, et al.
Publicado: (2020)

Good practices for (68)Ga radiopharmaceutical production
por: Nelson, Bryce J. B., et al.
Publicado: (2022)

[(68)Ga]Ga-PSMA-11: The First FDA-Approved (68)Ga-Radiopharmaceutical for PET Imaging of Prostate Cancer
por: Hennrich, Ute, et al.
Publicado: (2021)

(68)Ga-Based Radiopharmaceuticals: Production and Application Relationship
por: Velikyan, Irina
Publicado: (2015)

Cold Kit Labeling: The Future of (68)Ga Radiopharmaceuticals?
por: Lepareur, Nicolas
Publicado: (2022)

Instant kit preparation of (68)Ga-radiopharmaceuticals via the hybrid chelator DATA: clinical translation of [(68)Ga]Ga-DATA-TOC
por: Sinnes, Jean-Philippe, et al.
Publicado: (2019)

Design of CGMP Production of (18)F- and (68)Ga-Radiopharmaceuticals
por: Chi, Yen-Ting, et al.
Publicado: (2014)

New sensitive method for HEPES quantification in (68)Ga-radiopharmaceuticals
por: Antunes, I. F., et al.
Publicado: (2020)

Good practices for Ga-68 radiopharmaceutical production: an important correction
por: Gültekin, Aziz
Publicado: (2023)

A Specific HPLC Method to Determine Residual HEPES in [(68)Ga]Ga-Radiopharmaceuticals: Development and Validation
por: Migliari, Silvia, et al.
Publicado: (2022)

Corrigendum to “Design of CGMP Production of (18)F- and (68)Ga-Radiopharmaceuticals”
por: Chi, Yen-Ting, et al.
Publicado: (2016)

Multifarious Ga-68 Labeled PET Radiopharmaceuticals in Imaging Various Malignancies
por: Vatsa, Rakhee, et al.
Publicado: (2018)

Cyclotron Production of Gallium-68 Radiopharmaceuticals Using the (68)Zn(p,n)(68)Ga Reaction and Their Regulatory Aspects
por: Ashhar, Zarif, et al.
Publicado: (2022)

Novel Preclinical and Radiopharmaceutical Aspects of [(68)Ga]Ga-PSMA-HBED-CC: A New PET Tracer for Imaging of Prostate Cancer
por: Eder, Matthias, et al.
Publicado: (2014)

Cyclotron-based production of (68)Ga, [(68)Ga]GaCl(3), and [(68)Ga]Ga-PSMA-11 from a liquid target
por: Rodnick, Melissa E., et al.
Publicado: (2020)

Preclinical evaluation of two (68)Ga-siderophores as potential radiopharmaceuticals for Aspergillus fumigatus infection imaging
por: Petrik, Milos, et al.
Publicado: (2012)

Synthesis, Complexation Properties, and Evaluation of New Aminodiphosphonic Acids as Vector Molecules for (68)Ga Radiopharmaceuticals
por: Maruk, Alesya Ya., et al.
Publicado: (2021)

Incidental Meningioma on (68)Ga-DOTANOC Positron-Emission Tomography
por: Parihar, Ashwin Singh, et al.
Publicado: (2018)

[(68)Ga]Ga-Ornibactin for Burkholderia cepacia complex Infection Imaging Using Positron Emission Tomography
por: Bendova, Katerina, et al.
Publicado: (2023)

COVID-19 messenger ribonucleic acid vaccination and abnormal radiopharmaceutical uptake in the axilla visualized on (68)Ga-DOTATATE positron-emission tomography/computed tomography
por: Weissman, Joshua Philip, et al.
Publicado: (2021)

Automated GMP Production and Preclinical Evaluation of [(68)Ga]Ga-TEoS-DAZA and [(68)Ga]Ga-TMoS-DAZA
por: Greiser, Julia, et al.
Publicado: (2022)

Current Status of (68)Ga-Pentixafor in Solid Tumours
por: Hadebe, Bawinile, et al.
Publicado: (2022)

(68)Ga-DOTATATE-positron emission tomography imaging in spinal meningioma
por: Slotty, Philipp Jörg, et al.
Publicado: (2014)

Spinal molecular imaging by (68) Ga-DOTATATE-positron emission tomography
por: Sandu, Nora, et al.
Publicado: (2014)

(68)Ga-bisphosphonates for the imaging of extraosseous calcification by positron emission tomography
por: Keeling, George P., et al.
Publicado: (2023)

Meningiomas: A Comparative Study of (68)Ga-DOTATOC, (68)Ga-DOTANOC and (68)Ga-DOTATATE for Molecular Imaging in Mice
por: Soto-Montenegro, María Luisa, et al.
Publicado: (2014)

N-Benzylethanolammonium Ionic Liquids and Molten Salts in the Synthesis of (68)Ga- and Al(18)F-Labeled Radiopharmaceuticals
por: Kondratenko, Yulia A., et al.
Publicado: (2023)

Carbon Nanomaterials for Sorption of (68)Ga for Potential Using in Positron Emission Tomography
por: Kazakov, Andrey G., et al.
Publicado: (2020)

Graves' Ophthalmopathy on (68)Ga-DOTANOC Positron Emission Tomography/Computed Tomography
por: Arora, Saurabh, et al.
Publicado: (2019)

GMP-compliant production of [(68)Ga]Ga-NeoB for positron emission tomography imaging of patients with gastrointestinal stromal tumor
por: Pretze, Marc, et al.
Publicado: (2021)

Bn(2)DT3A, a Chelator for (68)Ga Positron Emission Tomography: Hydroxide Coordination Increases Biological Stability of [(68)Ga][Ga(Bn(2)DT3A)(OH)](−)
por: Price, Thomas W., et al.
Publicado: (2022)

Radiation exposure to nuclear medicine personnel handling positron emitters from Ge-68/Ga-68 generator
por: Dwivedi, Durgesh Kumar, et al.
Publicado: (2011)

Imaging of Pseudomonas aeruginosa infection with Ga-68 labelled pyoverdine for positron emission tomography
por: Petrik, Milos, et al.
Publicado: (2018)

A [68Ga]Ga-DOTANOC PET/CT Radiomic Model for Non-Invasive Prediction of Tumour Grade in Pancreatic Neuroendocrine Tumours
por: Bevilacqua, Alessandro, et al.
Publicado: (2021)

Liver PET Reloaded: Automated Synthesis of [(68)Ga]Ga-BP-IDA for Positron Imaging of the Hepatobiliary Function and First Clinical Experience
por: Werner, Anke, et al.
Publicado: (2023)

The role of [(68) Ga]Ga-DOTATATE PET/CT in wild-type KIT/PDGFRA gastrointestinal stromal tumours (GIST)
por: Aloj, Luigi, et al.
Publicado: (2021)

In vitro cytotoxicity of Auger electron-emitting [(67)Ga]Ga-trastuzumab
por: Othman, Muhamad Faiz bin, et al.
Publicado: (2020)

Voxel-based comparison of [(68)Ga]Ga-RM2-PET/CT and [(68)Ga]Ga-PSMA-11-PET/CT with histopathology for diagnosis of primary prostate cancer
por: Fassbender, Thomas Franz, et al.
Publicado: (2020)

A prospective head-to-head comparison of [(68)Ga]Ga-P16-093 and [(68)Ga]Ga-PSMA-11 PET/CT in patients with primary prostate cancer
por: Wang, Guochang, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_npmuphelm3rkqhmrsvgkqtknqt