A comparison of blood and brain‐derived ageing and inflammation‐related DNA methylation signatures and their association with microglial burdens

Inflammation and ageing‐related DNA methylation patterns in the blood have been linked to a variety of morbidities, including cognitive decline and neurodegenerative disease. However, it is unclear how these blood‐based patterns relate to patterns within the brain and how each associates with centra...

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Detalles Bibliográficos
Autores principales: Stevenson, Anna J., McCartney, Daniel L., Gadd, Danni A., Shireby, Gemma, Hillary, Robert F., King, Declan, Tzioras, Makis, Wrobel, Nicola, McCafferty, Sarah, Murphy, Lee, McColl, Barry W., Redmond, Paul, Taylor, Adele M., Harris, Sarah E., Russ, Tom C., McIntosh, Andrew M., Mill, Jonathan, Smith, Colin, Deary, Ian J., Cox, Simon R., Marioni, Riccardo E., Spires‐Jones, Tara L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Special Issue Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525452/
https://www.ncbi.nlm.nih.gov/pubmed/35362642
http://dx.doi.org/10.1111/ejn.15661

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