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PAF1 cooperates with YAP1 in metaplastic ducts to promote pancreatic cancer

Acinar-to-ductal metaplasia (ADM) is a precursor lesion of pancreatic ductal adenocarcinoma (PDAC); however, the regulators of the ADM-mediated PDAC development and its targeting are poorly understood. RNA polymerase II-associated factor 1 (PAF1) maintains cancer stem cells leading to the aggressive...

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Detalles Bibliográficos
Autores principales:	Nimmakayala, Rama Krishna, Ogunleye, Ayoola O., Parte, Seema, Krishna Kumar, Nivedeta, Raut, Pratima, Varadharaj, Venkatesh, Perumal, Naveen Kumar, Nallasamy, Palanisamy, Rauth, Sanchita, Cox, Jesse L., Lele, Subodh M., Batra, Surinder K., Ponnusamy, Moorthy P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525575/ https://www.ncbi.nlm.nih.gov/pubmed/36180487 http://dx.doi.org/10.1038/s41419-022-05258-x

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