Activating α7nAChR ameliorates abdominal aortic aneurysm through inhibiting pyroptosis mediated by NLRP3 inflammasome

Abdominal aortic aneurysm (AAA) is defined as a dilated aorta in diameter at least 1.5 times of a normal aorta. Our previous studies found that activating α7 nicotinic acetylcholine receptor (α7nAChR) had a protective effect on vascular injury. This work was to investigate whether activating α7nAChR...

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Detalles Bibliográficos
Autores principales: Fu, Hui, Shen, Qi-rui, Zhao, Yi, Ni, Min, Zhou, Can-can, Chen, Ji-kuai, Chi, Chen, Li, Dong-jie, Liang, Guang, Shen, Fu-ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525652/
https://www.ncbi.nlm.nih.gov/pubmed/35217818
http://dx.doi.org/10.1038/s41401-022-00876-9

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