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Sequential organ failure assessment score as a predictor of the outcomes of patients hospitalized for classical or exertional heatstroke

Heatstroke is a life-threatening event that affects people worldwide. Currently, there are no established tools to predict the outcomes of heatstroke. Although the Sequential Organ Failure Assessment (SOFA) score is a promising tool for judging the severity of critically ill patients. Therefore, in...

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Autores principales: Yokoyama, Kazuto, Kaneko, Tadashi, Ito, Asami, Ieki, Yohei, Kawamoto, Eiji, Suzuki, Kei, Ishikura, Ken, Imai, Hiroshi, Kanda, Jun, Yokobori, Shoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525654/
https://www.ncbi.nlm.nih.gov/pubmed/36180581
http://dx.doi.org/10.1038/s41598-022-20878-1
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author Yokoyama, Kazuto
Kaneko, Tadashi
Ito, Asami
Ieki, Yohei
Kawamoto, Eiji
Suzuki, Kei
Ishikura, Ken
Imai, Hiroshi
Kanda, Jun
Yokobori, Shoji
author_facet Yokoyama, Kazuto
Kaneko, Tadashi
Ito, Asami
Ieki, Yohei
Kawamoto, Eiji
Suzuki, Kei
Ishikura, Ken
Imai, Hiroshi
Kanda, Jun
Yokobori, Shoji
author_sort Yokoyama, Kazuto
collection PubMed
description Heatstroke is a life-threatening event that affects people worldwide. Currently, there are no established tools to predict the outcomes of heatstroke. Although the Sequential Organ Failure Assessment (SOFA) score is a promising tool for judging the severity of critically ill patients. Therefore, in this study, we investigated whether the SOFA score could predict the outcome of patients hospitalized with severe heatstroke, including the classical and exertional types, by using data from a Japanese nationwide multicenter observational registry. We performed retrospective subanalyses of the Japanese Association for Acute Medicine heatstroke registry, 2019. Adults with a SOFA score ≥ 1 hospitalized for heatstroke were analyzed. We analyzed data for 225 patients. Univariate and multivariable analyses showed a significant difference in the SOFA score between non-survivors and survivors in classical and exertional heatstroke cases. The area under the receiver operating characteristic curve were 0.863 (classical) and 0.979 (exertional). The sensitivity and specificity of SOFA scores were 50.0% and 97.5% (classical), 66.7% and 97.5% (exertional), respectively, at a cutoff of 12.5, and 35.0% and 98.8% (classical), 33.3% and 100.0% (exertional), respectively, at a cutoff of 13.5. This study revealed that the SOFA score may predict mortality in patients with heatstroke and might be useful for assessing prognosis.
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spelling pubmed-95256542022-10-02 Sequential organ failure assessment score as a predictor of the outcomes of patients hospitalized for classical or exertional heatstroke Yokoyama, Kazuto Kaneko, Tadashi Ito, Asami Ieki, Yohei Kawamoto, Eiji Suzuki, Kei Ishikura, Ken Imai, Hiroshi Kanda, Jun Yokobori, Shoji Sci Rep Article Heatstroke is a life-threatening event that affects people worldwide. Currently, there are no established tools to predict the outcomes of heatstroke. Although the Sequential Organ Failure Assessment (SOFA) score is a promising tool for judging the severity of critically ill patients. Therefore, in this study, we investigated whether the SOFA score could predict the outcome of patients hospitalized with severe heatstroke, including the classical and exertional types, by using data from a Japanese nationwide multicenter observational registry. We performed retrospective subanalyses of the Japanese Association for Acute Medicine heatstroke registry, 2019. Adults with a SOFA score ≥ 1 hospitalized for heatstroke were analyzed. We analyzed data for 225 patients. Univariate and multivariable analyses showed a significant difference in the SOFA score between non-survivors and survivors in classical and exertional heatstroke cases. The area under the receiver operating characteristic curve were 0.863 (classical) and 0.979 (exertional). The sensitivity and specificity of SOFA scores were 50.0% and 97.5% (classical), 66.7% and 97.5% (exertional), respectively, at a cutoff of 12.5, and 35.0% and 98.8% (classical), 33.3% and 100.0% (exertional), respectively, at a cutoff of 13.5. This study revealed that the SOFA score may predict mortality in patients with heatstroke and might be useful for assessing prognosis. Nature Publishing Group UK 2022-09-30 /pmc/articles/PMC9525654/ /pubmed/36180581 http://dx.doi.org/10.1038/s41598-022-20878-1 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Yokoyama, Kazuto
Kaneko, Tadashi
Ito, Asami
Ieki, Yohei
Kawamoto, Eiji
Suzuki, Kei
Ishikura, Ken
Imai, Hiroshi
Kanda, Jun
Yokobori, Shoji
Sequential organ failure assessment score as a predictor of the outcomes of patients hospitalized for classical or exertional heatstroke
title Sequential organ failure assessment score as a predictor of the outcomes of patients hospitalized for classical or exertional heatstroke
title_full Sequential organ failure assessment score as a predictor of the outcomes of patients hospitalized for classical or exertional heatstroke
title_fullStr Sequential organ failure assessment score as a predictor of the outcomes of patients hospitalized for classical or exertional heatstroke
title_full_unstemmed Sequential organ failure assessment score as a predictor of the outcomes of patients hospitalized for classical or exertional heatstroke
title_short Sequential organ failure assessment score as a predictor of the outcomes of patients hospitalized for classical or exertional heatstroke
title_sort sequential organ failure assessment score as a predictor of the outcomes of patients hospitalized for classical or exertional heatstroke
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525654/
https://www.ncbi.nlm.nih.gov/pubmed/36180581
http://dx.doi.org/10.1038/s41598-022-20878-1
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