Quaternary structure of patient-homogenate amplified α-synuclein fibrils modulates seeding of endogenous α-synuclein

Parkinson’s disease (PD) and Multiple System Atrophy (MSA) are progressive and unremitting neurological diseases that are neuropathologically characterized by α-synuclein inclusions. Increasing evidence supports the aggregation of α-synuclein in specific brain areas early in the disease course, foll...

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Detalles Bibliográficos
Autores principales: Frieg, Benedikt, Geraets, James A., Strohäker, Timo, Dienemann, Christian, Mavroeidi, Panagiota, Jung, Byung Chul, Kim, Woojin S., Lee, Seung-Jae, Xilouri, Maria, Zweckstetter, Markus, Schröder, Gunnar F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525671/
https://www.ncbi.nlm.nih.gov/pubmed/36180728
http://dx.doi.org/10.1038/s42003-022-03948-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525671/
https://www.ncbi.nlm.nih.gov/pubmed/36180728
http://dx.doi.org/10.1038/s42003-022-03948-y

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