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Amiodarone improves anemia in a murine model of sickle cell disease and is associated with increased erythrocyte bis(monoacylglycerol) phosphate

Sickle cell disease (SCD) is associated with altered plasma and erythrocyte lipid profiles. In a previous study, SCD mice with deficiency of proprotein convertase subtilisin/kexin type 9 (PCSK9) were observed to have more severe anemia and increased sickling compared to control SCD mice. Although PC...

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Detalles Bibliográficos
Autores principales: Venugopal, Jessica, Wang, Jintao, Guo, Chiao, Eitzman, Daniel T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525675/
https://www.ncbi.nlm.nih.gov/pubmed/36180774
http://dx.doi.org/10.1038/s41598-022-20955-5

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