Identification of hydantoin based Decaprenylphosphoryl-β-d-Ribose Oxidase (DprE1) inhibitors as antimycobacterial agents using computational tools

Tuberculosis (TB) is one of the emerging infectious diseases in the world. DprE1 (Decaprenylphosphoryl-β-d-ribose 2′-epimerase), an enzyme accountable for mycobacterial cell wall synthesis was the first drug gable target based on discoveries of inhibitors via HTS (high throughput screening). Since t...

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Detalles Bibliográficos
Autores principales: Mali, Suraj N., Pandey, Anima, Bhandare, Richie R., Shaik, Afzal B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525719/
https://www.ncbi.nlm.nih.gov/pubmed/36180452
http://dx.doi.org/10.1038/s41598-022-20325-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525719/
https://www.ncbi.nlm.nih.gov/pubmed/36180452
http://dx.doi.org/10.1038/s41598-022-20325-1

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