Cargando…

The mIAA7 degron improves auxin-mediated degradation in Caenorhabditis elegans

Auxin-inducible degradation is a powerful tool for the targeted degradation of proteins with spatiotemporal control. One limitation of the auxin-inducible degradation system is that not all proteins are degraded efficiently. Here, we demonstrate that an alternative degron sequence, termed mIAA7, imp...

Descripción completa

Detalles Bibliográficos
Autores principales: Sepers, Jorian J, Verstappen, Noud H M, Vo, An A, Ragle, James Matthew, Ruijtenberg, Suzan, Ward, Jordan D, Boxem, Mike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526053/
https://www.ncbi.nlm.nih.gov/pubmed/36029236
http://dx.doi.org/10.1093/g3journal/jkac222