Inhibition of HIPK2 protects stress-induced pathological cardiac remodeling

BACKGROUND: Homeodomain-Interacting Protein Kinase 2 (HIPK2) has been reported to maintain basal cardiac function, however, its role in pathological cardiac remodeling remains unclear. METHODS: HIPK2 inhibitors (tBID and PKI1H) treated mice and two lines of HIPK2(−/−) mice were subjected to transver...

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Detalles Bibliográficos
Autores principales: Zhou, Qiulian, Meng, Danni, Li, Feng, Zhang, Xiao, Liu, Li, Zhu, Yujiao, Liu, Shuqin, Xu, Minjun, Deng, Jiali, Lei, Zhiyong, Sluijter, Joost P.G., Xiao, Junjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526139/
https://www.ncbi.nlm.nih.gov/pubmed/36182775
http://dx.doi.org/10.1016/j.ebiom.2022.104274

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