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Causal analysis identifies small HDL particles and physical activity as key determinants of longevity of older adults
BACKGROUND: The hard endpoint of death is one of the most significant outcomes in both clinical practice and research settings. Our goal was to discover direct causes of longevity from medically accessible data. METHODS: Using a framework that combines local causal discovery algorithms with discover...
Autores principales: | Kraus, Virginia Byers, Ma, Sisi, Tourani, Roshan, Fillenbaum, Gerda G., Burchett, Bruce M., Parker, Daniel C., Kraus, William E., Connelly, Margery A., Otvos, James D., Cohen, Harvey Jay, Orenduff, Melissa C., Pieper, Carl F., Zhang, Xin, Aliferis, Constantin F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526168/ https://www.ncbi.nlm.nih.gov/pubmed/36182774 http://dx.doi.org/10.1016/j.ebiom.2022.104292 |
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