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Comparative effectiveness of valproic acid in different serum concentrations for maintenance treatment of bipolar disorder: A retrospective cohort study using target trial emulation framework

BACKGROUND: There is a lack of consensus on the optimal serum valproic acid (VPA) concentration for maintenance therapy in bipolar disorder (BD). We aimed to investigate the association between serum VPA levels and risk of mood episode recurrence. METHODS: We enrolled patients with BD from multiple...

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Detalles Bibliográficos
Autores principales: Chen, Yang-Chieh Brian, Liang, Chih-Sung, Wang, Liang-Jen, Hung, Kuo-Chuan, Carvalho, Andre F., Solmi, Marco, Vieta, Eduard, Tseng, Ping-Tao, Lin, Pao-Yen, Tu, Yu-Kang, Hsu, Chih-Wei, Lai, Edward Chia-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526172/
https://www.ncbi.nlm.nih.gov/pubmed/36193173
http://dx.doi.org/10.1016/j.eclinm.2022.101678