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Risk factors for hemodynamic instability during laparoscopic resection of pheochromocytoma
BACKGROUND: Laparoscopic adrenalectomy for pheochromocytoma is associated with high risk of intraoperative hemodynamic instability. Our study aimed to identify predictive factors for hemodynamic instability during laparoscopic resection of pheochromocytoma. METHODS: Between January 2011 and December...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526242/ https://www.ncbi.nlm.nih.gov/pubmed/36180851 http://dx.doi.org/10.1186/s12894-022-01109-1 |
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author | Huang, Yong-sheng Yan, Lei Li, Ze-yan Fang, Zhi-qing Liu, Zhao Xu, Zhong-hua Gu, Gang-Li |
author_facet | Huang, Yong-sheng Yan, Lei Li, Ze-yan Fang, Zhi-qing Liu, Zhao Xu, Zhong-hua Gu, Gang-Li |
author_sort | Huang, Yong-sheng |
collection | PubMed |
description | BACKGROUND: Laparoscopic adrenalectomy for pheochromocytoma is associated with high risk of intraoperative hemodynamic instability. Our study aimed to identify predictive factors for hemodynamic instability during laparoscopic resection of pheochromocytoma. METHODS: Between January 2011 and December 2021, 136 patients underwent unilateral laparoscopic adrenalectomy for pheochromocytoma. The patients were divided into 2 groups depending on the presence or absence of hemodynamic instability during surgery. Intraoperative hemodynamic parameters were compared between the 2 groups. Patient demographic characteristics and preoperative evaluations were assessed for their prognostic relevance with respect to intraoperative hemodynamic instability via both univariate analysis and multivariate logistic regression analysis. RESULTS: There was greater blood pressure fluctuations and higher maximum blood pressure and heart rate in the hemodynamic instability group. More patients need intraoperative administration of vasoactive drugs in the hemodynamic instability group. In the univariate analysis, presence of coronary artery disease, tumour size, and previous hypertension history were significantly associated with intraoperative hemodynamic instability. The multivariate logistic regression analysis showed that tumour size and previous hypertension history were independent risk factors for intraoperative hemodynamic instability. CONCLUSION: Tumour size and previous hypertension history were associated with hemodynamic instability during laparoscopic resection of pheochromocytoma. |
format | Online Article Text |
id | pubmed-9526242 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-95262422022-10-02 Risk factors for hemodynamic instability during laparoscopic resection of pheochromocytoma Huang, Yong-sheng Yan, Lei Li, Ze-yan Fang, Zhi-qing Liu, Zhao Xu, Zhong-hua Gu, Gang-Li BMC Urol Research BACKGROUND: Laparoscopic adrenalectomy for pheochromocytoma is associated with high risk of intraoperative hemodynamic instability. Our study aimed to identify predictive factors for hemodynamic instability during laparoscopic resection of pheochromocytoma. METHODS: Between January 2011 and December 2021, 136 patients underwent unilateral laparoscopic adrenalectomy for pheochromocytoma. The patients were divided into 2 groups depending on the presence or absence of hemodynamic instability during surgery. Intraoperative hemodynamic parameters were compared between the 2 groups. Patient demographic characteristics and preoperative evaluations were assessed for their prognostic relevance with respect to intraoperative hemodynamic instability via both univariate analysis and multivariate logistic regression analysis. RESULTS: There was greater blood pressure fluctuations and higher maximum blood pressure and heart rate in the hemodynamic instability group. More patients need intraoperative administration of vasoactive drugs in the hemodynamic instability group. In the univariate analysis, presence of coronary artery disease, tumour size, and previous hypertension history were significantly associated with intraoperative hemodynamic instability. The multivariate logistic regression analysis showed that tumour size and previous hypertension history were independent risk factors for intraoperative hemodynamic instability. CONCLUSION: Tumour size and previous hypertension history were associated with hemodynamic instability during laparoscopic resection of pheochromocytoma. BioMed Central 2022-09-30 /pmc/articles/PMC9526242/ /pubmed/36180851 http://dx.doi.org/10.1186/s12894-022-01109-1 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Huang, Yong-sheng Yan, Lei Li, Ze-yan Fang, Zhi-qing Liu, Zhao Xu, Zhong-hua Gu, Gang-Li Risk factors for hemodynamic instability during laparoscopic resection of pheochromocytoma |
title | Risk factors for hemodynamic instability during laparoscopic resection of pheochromocytoma |
title_full | Risk factors for hemodynamic instability during laparoscopic resection of pheochromocytoma |
title_fullStr | Risk factors for hemodynamic instability during laparoscopic resection of pheochromocytoma |
title_full_unstemmed | Risk factors for hemodynamic instability during laparoscopic resection of pheochromocytoma |
title_short | Risk factors for hemodynamic instability during laparoscopic resection of pheochromocytoma |
title_sort | risk factors for hemodynamic instability during laparoscopic resection of pheochromocytoma |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526242/ https://www.ncbi.nlm.nih.gov/pubmed/36180851 http://dx.doi.org/10.1186/s12894-022-01109-1 |
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