Group sequential designs in pragmatic trials: feasibility and assessment of utility using data from a number of recent surgical RCTs

BACKGROUND: Assessing the long term effects of many surgical interventions tested in pragmatic RCTs may require extended periods of participant follow-up to assess effectiveness and use patient-reported outcomes that require large sample sizes. Consequently the RCTs are often perceived as being expe...

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Detalles Bibliográficos
Autores principales: Parsons, Nick R., Stallard, Nigel, Parsons, Helen, Haque, Aminul, Underwood, Martin, Mason, James, Khan, Iftekhar, Costa, Matthew L., Griffin, Damian R., Griffin, James, Beard, David J., Cook, Jonathan A., Davies, Loretta, Hudson, Jemma, Metcalfe, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526271/
https://www.ncbi.nlm.nih.gov/pubmed/36183085
http://dx.doi.org/10.1186/s12874-022-01734-2

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