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Dramatic impacts on brain pathology, anxiety, and cognitive function in the knock-in APP(NL-G-F) mouse model of Alzheimer disease following long-term voluntary exercise

BACKGROUND: An active lifestyle is associated with improved cognitive functions in aged people and may prevent or slow down the progression of various neurodegenerative diseases including Alzheimer’s disease (AD). To investigate these protective effects, male APP(NL-G-F) mice were exposed to long-te...

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Detalles Bibliográficos
Autores principales:	Mehla, Jogender, Deibel, Scott H., Karem, Hadil, Hossain, Shakhawat, Lacoursiere, Sean G., Sutherland, Robert J., Mohajerani, Majid H., McDonald, Robert J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526288/ https://www.ncbi.nlm.nih.gov/pubmed/36180883 http://dx.doi.org/10.1186/s13195-022-01085-6

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