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BTK inhibitors in the treatment of hematological malignancies and inflammatory diseases: mechanisms and clinical studies
Bruton’s tyrosine kinase (BTK) is an essential component of multiple signaling pathways that regulate B cell and myeloid cell proliferation, survival, and functions, making it a promising therapeutic target for various B cell malignancies and inflammatory diseases. Five small molecule inhibitors hav...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526392/ https://www.ncbi.nlm.nih.gov/pubmed/36183125 http://dx.doi.org/10.1186/s13045-022-01353-w |