Characterization of Genetic Variants Associated with Rifampicin Resistance Level in Mycobacterium tuberculosis Clinical Isolates Collected in Guangzhou Chest Hospital, China

OBJECTIVE: Rifampicin (RIF)-resistance, a surrogate marker for multidrug-resistant tuberculosis (TB), is mediated by mutations in the rpoB gene. We aimed to investigate the prevalence of mutations pattern in the entire rpoB gene of Mycobacterium tuberculosis clinical isolates and their association w...

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Detalles Bibliográficos
Autores principales: Hameed, H M Adnan, Fang, Cuiting, Liu, Zhiyong, Ju, Yanan, Han, Xingli, Gao, Yamin, Wang, Shuai, Chiwala, Gift, Tan, Yaoju, Guan, Ping, Hu, Jinxing, Xiong, Xiaoli, Peng, Jiacong, Lin, Yongping, Hussain, Muzammal, Zhong, Nanshan, Maslov, Dmitry A, Cook, Gregory M, Liu, Jianxiong, Zhang, Tianyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526423/
https://www.ncbi.nlm.nih.gov/pubmed/36193294
http://dx.doi.org/10.2147/IDR.S375869

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