Cargando…

Genetic Polymorphisms in miR-137 and Its Target Genes, TCF4 and CACNA1C, Contribute to the Risk of Bipolar Disorder: A Preliminary Case-Control Study and Bioinformatics Analysis

Accumulating evidence has suggested that miR-137 and its target genes, CACNA1C, and TCF4, are amongst the most robustly implicated genes in psychiatric disorders. This preliminary study is aimed at investigating the effects of genetic variations in miR-137 (rs1625579A/C), TCF4 (rs1261084C/T), and CA...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mokhtari, Mohammad Ali, Sargazi, Saman, Saravani, Ramin, Heidari Nia, Milad, Mirinejad, Shekoufeh, Hadzsiev, Kinga, Bene, Judit, Shakiba, Mansoor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526595/ https://www.ncbi.nlm.nih.gov/pubmed/36193501 http://dx.doi.org/10.1155/2022/1886658

Ejemplares similares

Relationship between Single Nucleotide Polymorphisms of GRHL3 and Schizophrenia Susceptibility: A Preliminary Case-Control Study and Bioinformatics Analysis
por: Sargazi, Saman, et al.
Publicado: (2020)

Impact of Proliferator-Activated Receptor γ Gene Polymorphisms on Risk of Schizophrenia: A Case-Control Study and Computational Analyses
por: Sargazi, Saman, et al.
Publicado: (2020)

Association of a Novel KIF26B Gene Polymorphism with Susceptibility to Schizophrenia and Breast Cancer: A Case-Control Study
por: SARGAZI, Saman, et al.
Publicado: (2021)

Association of Polymorphisms within HOX Transcript Antisense RNA (HOTAIR) with Type 2 Diabetes Mellitus and Laboratory Characteristics: A Preliminary Case-Control Study
por: Sargazi, Saman, et al.
Publicado: (2022)

Association of TMPRSS2 Gene Polymorphisms with COVID-19 Severity and Mortality: a Case-Control Study with Computational Analyses
por: Rokni, Mohsen, et al.
Publicado: (2022)

Association of SLC11A1 polymorphisms with anthropometric and biochemical parameters describing Type 2 Diabetes Mellitus
por: Kavian, Zahra, et al.
Publicado: (2023)

Hydro-alcoholic Extract of Achillea Wilhelmsii C. Koch Reduces the Expression of Cell Death-Associated Genes while Inducing DNA Damage in HeLa Cervical Cancer Cells
por: Sargazi, Saman, et al.
Publicado: (2020)

Relationship between common interleukin 1-beta gene polymorphisms and the risk of gestational disorders: An updated meta-analysis
por: Harati-Sadegh, Mahdiyeh, et al.
Publicado: (2021)

Association of Polymorphisms in miR146a, an Inflammation-Associated MicroRNA, with the Risk of Idiopathic Recurrent Spontaneous Miscarriage: A Case-Control Study
por: Salimi, Saeedeh, et al.
Publicado: (2022)

Association of IL-1Ra Ser133Ser Variant with Susceptibility to Immune-Mediated and Inflammatory Diseases: A Meta-Analysis of 2622 Cases and 3854 Controls
por: HARATI-SADEGH, Mahdiyeh, et al.
Publicado: (2020)

Induction of apoptosis and modulation of homologous recombination DNA repair pathway in prostate cancer cells by the combination of AZD2461 and valproic acid
por: Sargazi, Saman, et al.
Publicado: (2019)

Mild antagonistic effect of Valproic acid in combination with AZD2461 in MCF-7 breast cancer cells
por: Sargazi, Saman, et al.
Publicado: (2019)

Relationship between P2XR4 Gene Variants and the Risk of Schizophrenia in South-East of Iran: A Preliminary Case-Control Study and in Silico Analysis
por: Nia, Milad Heidari, et al.
Publicado: (2021)

Silencing of Nucleostemin by siRNA Induces Apoptosis in MCF-7 and MDA-MB-468 Cell Lines
por: Moudi, Mahdiyeh, et al.
Publicado: (2020)

Adrenal Insufficiency in Patients with Beta-Thalassemia Major in the Southeast of Iran
por: Miri-Aliabad, Ghasem, et al.
Publicado: (2022)

Role of carnitine and its derivatives in the development and management of type 2 diabetes
por: Bene, Judit, et al.
Publicado: (2018)

Copy Number Variations in Neuropsychiatric Disorders
por: Büki, Gergely, et al.
Publicado: (2023)

Hydroalcoholic Extract of Levisticum officinale Increases cGMP Signaling Pathway by Down-Regulating PDE5 Expression and Induction of Apoptosis in MCF-7 and MDA-MB-468 Breast Cancer Cell Lines
por: Sargazi, Marzieh Lotfian, et al.
Publicado: (2019)

CACNA1C hypermethylation is associated with bipolar disorder
por: Starnawska, A, et al.
Publicado: (2016)

Catechol-O-Methyltransferase (COMT) Gene (Val158Met) and Brain-Derived Neurotropic Factor (BDNF) (Val66Met) Genes Polymorphism in Schizophrenia: A Case-Control Study
por: Saravani, Ramin, et al.
Publicado: (2017)

Correlation between large FBN1 deletions and severe cardiovascular phenotype in Marfan syndrome: Analysis of two novel cases and analytical review of the literature
por: Buki, Gergely, et al.
Publicado: (2023)

Novel Poly(Adenosine Diphosphate-Ribose) Polymerase (PARP) Inhibitor, AZD2461, Down-Regulates VEGF and Induces Apoptosis in Prostate Cancer Cells
por: Sargazi, Saman, et al.
Publicado: (2019)

Association of CACNA1C Variants with Bipolar Disorder in the Korean Population
por: Kim, Soojin, et al.
Publicado: (2016)

A rare mutation of CACNA1C in a patient with Bipolar disorder, and decreased gene expression associated with a Bipolar-associated common SNP of CACNA1C in brain
por: Gershon, Elliot S., et al.
Publicado: (2013)

Superimposed Mosaicism in the Form of Extremely Extended Segmental Plexiform Neurofibroma Caused by a Novel Pathogenic Variant in the NF1 Gene
por: Veres, Klára, et al.
Publicado: (2023)

Three-Year Follow-Up after Intrauterine mTOR Inhibitor Administration for Fetus with TSC-Associated Rhabdomyoma
por: Maász, Anita, et al.
Publicado: (2023)

The effects of omega 3 fatty acids on the serum concentrations of pro inflammatory cytokines anddepression status in patients with bipolar disorder: A randomized double-blind controlled clinical trial
por: Eslahi, Hadi, et al.
Publicado: (2023)

PS43. Association of CACNA1C Variants with Bipolar Disorder in the Korean Population
por: Kim, Soojin, et al.
Publicado: (2016)

Identification of an NF1 Microdeletion with Optical Genome Mapping
por: Büki, Gergely, et al.
Publicado: (2023)

CACNA1C Risk Variant and Amygdala Activity in Bipolar Disorder, Schizophrenia and Healthy Controls
por: Tesli, Martin, et al.
Publicado: (2013)

No effect of schizophrenia risk genes MIR137, TCF4, and ZNF804A on macroscopic brain structure
por: Cousijn, Helena, et al.
Publicado: (2014)

Correction: CACNA1C Risk Variant and Amygdala Activity in Bipolar Disorder, Schizophrenia and Healthy Controls
por: Tesli, Martin, et al.
Publicado: (2013)

The association of genetic variation in CACNA1C with resting-state functional connectivity in youth bipolar disorder
por: Jiang, Xinyue, et al.
Publicado: (2023)

The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia
por: Green, E K, et al.
Publicado: (2010)

Analysis of ANK3 and CACNA1C variants identified in bipolar disorder whole genome sequence data
por: Fiorentino, Alessia, et al.
Publicado: (2014)

Co-occurrence of neurofibromatosis type 1 and pseudoachondroplasia – a first case report
por: Pálla, Sára, et al.
Publicado: (2023)

Mutation analysis of CACNA1A gene in Iranian migrainous and review literatures
por: Meamar, Rokhsareh, et al.
Publicado: (2013)

Genome-Wide Supported Risk Variants in MIR137, CACNA1C, CSMD1, DRD2, and GRM3 Contribute to Schizophrenia Susceptibility in Pakistani Population
por: Fatima, Ambrin, et al.
Publicado: (2017)

miR-137 targets the inhibition of TCF4 to reverse the progression of osteoarthritis through the AMPK/NF-κB signaling pathway
por: Wang, Jinyu, et al.
Publicado: (2020)

CACNA1C Risk Variant and Mood Stabilizers Effects in the Prefrontal Cortical Thickness of Mexican Patients with Bipolar Disorder
por: Rodríguez-Ramírez, Alejandra Monserrat, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_gfcm7vb4vrif689tiqngklgv0s