Cargando…

The Role of Natural Products as Inhibitors of JAK/STAT Signaling Pathways in Glioblastoma Treatment

The permeability of glioblastoma, as well as its escaping the immune system, makes them one of the most deadly human malignancies. By avoiding programmed cell death (apoptosis), unlimited cell growth and metastatic ability could dramatically affect the immune system. Genetic mutations, epigenetic ch...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fahmideh, Hanieh, Shapourian, Hooriyeh, Moltafeti, Rasol, Tavakol, Chanour, Forghaniesfidvajani, Razieh, Zalpoor, Hamidreza, Nabi-Afjadi, Mohsen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526628/ https://www.ncbi.nlm.nih.gov/pubmed/36193062 http://dx.doi.org/10.1155/2022/7838583

Ejemplares similares

Quercetin as a JAK–STAT inhibitor: a potential role in solid tumors and neurodegenerative diseases
por: Zalpoor, Hamidreza, et al.
Publicado: (2022)

Hesperetin as an anti-SARS-CoV-2 agent can inhibit COVID-19-associated cancer progression by suppressing intracellular signaling pathways
por: Zalpoor, Hamidreza, et al.
Publicado: (2022)

Hypoxia‐inducible factor 1 alpha (HIF‐1α) stimulated and P2X7 receptor activated by COVID-19, as a potential therapeutic target and risk factor for epilepsy
por: Zalpoor, Hamidreza, et al.
Publicado: (2022)

The role of bone marrow microenvironment (BMM) cells in acute myeloid leukemia (AML) progression: immune checkpoints, metabolic checkpoints, and signaling pathways
por: Bakhtiyari, Maryam, et al.
Publicado: (2023)

The roles of metabolic profiles and intracellular signaling pathways of tumor microenvironment cells in angiogenesis of solid tumors
por: Zalpoor, Hamidreza, et al.
Publicado: (2022)

Increased neuropilin-1 expression by COVID-19: a possible cause of long-term neurological complications and progression of primary brain tumors
por: Zalpoor, Hamidreza, et al.
Publicado: (2022)

Ephrin (Eph) receptor and downstream signaling pathways: a promising potential targeted therapy for COVID‑19 and associated cancers and diseases
por: Zalpoor, Hamidreza, et al.
Publicado: (2022)

Diabetes as one of the long-term COVID-19 complications: from the potential reason of more diabetic patients’ susceptibility to COVID-19 to the possible caution of future global diabetes tsunami
por: Sharbatdar, Yasamin, et al.
Publicado: (2023)

CD147 and cyclophilin A: a promising potential targeted therapy for COVID-19 and associated cancer progression and chemo-resistance
por: Bakhtiyari, Maryam, et al.
Publicado: (2023)

The roles of Eph receptors, neuropilin-1, P2X7, and CD147 in COVID-19-associated neurodegenerative diseases: inflammasome and JaK inhibitors as potential promising therapies
por: Zalpoor, Hamidreza, et al.
Publicado: (2022)

Association of MicroRNA-146a with Type 1 and 2 Diabetes and their Related Complications
por: Ghaffari, Mahyar, et al.
Publicado: (2023)

Potential role of autophagy induced by FLT3-ITD and acid ceramidase in acute myeloid leukemia chemo-resistance: new insights
por: Zalpoor, Hamidreza, et al.
Publicado: (2022)

Lectins and lectibodies: potential promising antiviral agents
por: Nabi-Afjadi, Mohsen, et al.
Publicado: (2022)

The correlation between Flt3-ITD mutation in dendritic cells with TIM-3 expression in acute myeloid leukemia
por: Shapoorian, Hooriyeh, et al.
Publicado: (2021)

Renal aspergillosis after COVID‐19‐associated pulmonary aspergillosis: A case report
por: Ghasemian, Roya, et al.
Publicado: (2023)

A cellular and molecular biology-based update for ivermectin against COVID-19: is it effective or non-effective?
por: Nabi-Afjadi, Mohsen, et al.
Publicado: (2023)

The role of tumor microenvironment on cancer stem cell fate in solid tumors
por: Razi, Sara, et al.
Publicado: (2023)

The Role and Therapeutic Targeting of JAK/STAT Signaling in Glioblastoma
por: Ou, Alexander, et al.
Publicado: (2021)

Effect of the JAK2/STAT3 inhibitor SAR317461 on human glioblastoma tumorspheres
por: Mukthavaram, Rajesh, et al.
Publicado: (2015)

Exosome application in treatment and diagnosis of B-cell disorders: leukemias, multiple sclerosis, and arthritis rheumatoid
por: Karami Fath, Mohsen, et al.
Publicado: (2022)

JAK-STAT pathway inhibitors in dermatology()
por: Miot, Hélio Amante, et al.
Publicado: (2023)

Anti-cancer peptide-based therapeutic strategies in solid tumors
por: Karami Fath, Mohsen, et al.
Publicado: (2022)

Current understanding of epigenetics role in melanoma treatment and resistance
por: Karami Fath, Mohsen, et al.
Publicado: (2022)

The role of epigenetic modifications in drug resistance and treatment of breast cancer
por: Karami Fath, Mohsen, et al.
Publicado: (2022)

Methotrexate Is a JAK/STAT Pathway Inhibitor
por: Thomas, Sally, et al.
Publicado: (2015)

“Do We Know Jack” About JAK? A Closer Look at JAK/STAT Signaling Pathway
por: Bousoik, Emira, et al.
Publicado: (2018)

Dysregulation of JAK-STAT pathway in hematological malignancies and JAK inhibitors for clinical application
por: Furqan, Muhammad, et al.
Publicado: (2013)

The Use of JAK/STAT Inhibitors in Chronic Inflammatory Disorders
por: Caiazzo, Giuseppina, et al.
Publicado: (2023)

Heterodimeric JAK-STAT Activation as a Mechanism of Persistence to JAK2 Inhibitor Therapy
por: Koppikar, Priya, et al.
Publicado: (2012)

The JAK inhibitor tofacitinib suppresses synovial JAK1-STAT signalling in rheumatoid arthritis
por: Boyle, D L, et al.
Publicado: (2015)

JAK/STAT Pathway Mutations in T-ALL, Including the STAT5B N642H Mutation, are Sensitive to JAK1/JAK3 Inhibitors
por: Govaerts, Inge, et al.
Publicado: (2019)

JAKs and STATs in chemoresistance
por: Costa-Pereira, Ana P
Publicado: (2010)

JAK-STAT and feeding
por: Ladyman, Sharon R., et al.
Publicado: (2013)

A comprehensive review of COVID-19 characteristics
por: Esakandari, Hanie, et al.
Publicado: (2020)

The impact of JAK/STAT inhibitor ruxolitinib on the genesis of lymphoproliferative diseases
por: TÜRK, Can, et al.
Publicado: (2019)

Small Molecule Inhibitors of Interferon‐Induced JAK‐STAT Signalling
por: Thoidingjam, Leishemba K., et al.
Publicado: (2022)

Effect of the JAK/STAT Inhibitor Tofacitinib on Macrophage Cholesterol Metabolism
por: Adorni, Maria Pia, et al.
Publicado: (2023)

Protein Inhibitor of Activated STAT (PIAS) Negatively Regulates the JAK/STAT Pathway by Inhibiting STAT Phosphorylation and Translocation
por: Niu, Guo-Juan, et al.
Publicado: (2018)

Proteomimetics of Natural Regulators of JAK–STAT Pathway: Novel Therapeutic Perspectives
por: La Manna, Sara, et al.
Publicado: (2022)

Molecular Mechanisms Involved in Intrarenal Renin-Angiotensin and Alternative Pathways in Diabetic Nephropathy - A Review
por: Bahreini, Elham, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_tstr125sdbu8mg10sb8ug0ciac