Cargando…
Fully automated preoperative liver volumetry incorporating the anatomical location of the central hepatic vein
The precise preoperative calculation of functional liver volumes is essential prior major liver resections, as well as for the evaluation of a suitable donor for living donor liver transplantation. The aim of this study was to develop a fully automated, reproducible, and quantitative 3D volumetry of...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526715/ https://www.ncbi.nlm.nih.gov/pubmed/36183002 http://dx.doi.org/10.1038/s41598-022-20778-4 |
_version_ | 1784800941811171328 |
---|---|
author | Koitka, Sven Gudlin, Phillip Theysohn, Jens M. Oezcelik, Arzu Hoyer, Dieter P. Dayangac, Murat Hosch, René Haubold, Johannes Flaschel, Nils Nensa, Felix Malamutmann, Eugen |
author_facet | Koitka, Sven Gudlin, Phillip Theysohn, Jens M. Oezcelik, Arzu Hoyer, Dieter P. Dayangac, Murat Hosch, René Haubold, Johannes Flaschel, Nils Nensa, Felix Malamutmann, Eugen |
author_sort | Koitka, Sven |
collection | PubMed |
description | The precise preoperative calculation of functional liver volumes is essential prior major liver resections, as well as for the evaluation of a suitable donor for living donor liver transplantation. The aim of this study was to develop a fully automated, reproducible, and quantitative 3D volumetry of the liver from standard CT examinations of the abdomen as part of routine clinical imaging. Therefore, an in-house dataset of 100 venous phase CT examinations for training and 30 venous phase ex-house CT examinations with a slice thickness of 5 mm for testing and validating were fully annotated with right and left liver lobe. Multi-Resolution U-Net 3D neural networks were employed for segmenting these liver regions. The Sørensen-Dice coefficient was greater than 0.9726 ± 0.0058, 0.9639 ± 0.0088, and 0.9223 ± 0.0187 and a mean volume difference of 32.12 ± 19.40 ml, 22.68 ± 21.67 ml, and 9.44 ± 27.08 ml compared to the standard of reference (SoR) liver, right lobe, and left lobe annotation was achieved. Our results show that fully automated 3D volumetry of the liver on routine CT imaging can provide reproducible, quantitative, fast and accurate results without needing any examiner in the preoperative work-up for hepatobiliary surgery and especially for living donor liver transplantation. |
format | Online Article Text |
id | pubmed-9526715 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-95267152022-10-03 Fully automated preoperative liver volumetry incorporating the anatomical location of the central hepatic vein Koitka, Sven Gudlin, Phillip Theysohn, Jens M. Oezcelik, Arzu Hoyer, Dieter P. Dayangac, Murat Hosch, René Haubold, Johannes Flaschel, Nils Nensa, Felix Malamutmann, Eugen Sci Rep Article The precise preoperative calculation of functional liver volumes is essential prior major liver resections, as well as for the evaluation of a suitable donor for living donor liver transplantation. The aim of this study was to develop a fully automated, reproducible, and quantitative 3D volumetry of the liver from standard CT examinations of the abdomen as part of routine clinical imaging. Therefore, an in-house dataset of 100 venous phase CT examinations for training and 30 venous phase ex-house CT examinations with a slice thickness of 5 mm for testing and validating were fully annotated with right and left liver lobe. Multi-Resolution U-Net 3D neural networks were employed for segmenting these liver regions. The Sørensen-Dice coefficient was greater than 0.9726 ± 0.0058, 0.9639 ± 0.0088, and 0.9223 ± 0.0187 and a mean volume difference of 32.12 ± 19.40 ml, 22.68 ± 21.67 ml, and 9.44 ± 27.08 ml compared to the standard of reference (SoR) liver, right lobe, and left lobe annotation was achieved. Our results show that fully automated 3D volumetry of the liver on routine CT imaging can provide reproducible, quantitative, fast and accurate results without needing any examiner in the preoperative work-up for hepatobiliary surgery and especially for living donor liver transplantation. Nature Publishing Group UK 2022-10-01 /pmc/articles/PMC9526715/ /pubmed/36183002 http://dx.doi.org/10.1038/s41598-022-20778-4 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Koitka, Sven Gudlin, Phillip Theysohn, Jens M. Oezcelik, Arzu Hoyer, Dieter P. Dayangac, Murat Hosch, René Haubold, Johannes Flaschel, Nils Nensa, Felix Malamutmann, Eugen Fully automated preoperative liver volumetry incorporating the anatomical location of the central hepatic vein |
title | Fully automated preoperative liver volumetry incorporating the anatomical location of the central hepatic vein |
title_full | Fully automated preoperative liver volumetry incorporating the anatomical location of the central hepatic vein |
title_fullStr | Fully automated preoperative liver volumetry incorporating the anatomical location of the central hepatic vein |
title_full_unstemmed | Fully automated preoperative liver volumetry incorporating the anatomical location of the central hepatic vein |
title_short | Fully automated preoperative liver volumetry incorporating the anatomical location of the central hepatic vein |
title_sort | fully automated preoperative liver volumetry incorporating the anatomical location of the central hepatic vein |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526715/ https://www.ncbi.nlm.nih.gov/pubmed/36183002 http://dx.doi.org/10.1038/s41598-022-20778-4 |
work_keys_str_mv | AT koitkasven fullyautomatedpreoperativelivervolumetryincorporatingtheanatomicallocationofthecentralhepaticvein AT gudlinphillip fullyautomatedpreoperativelivervolumetryincorporatingtheanatomicallocationofthecentralhepaticvein AT theysohnjensm fullyautomatedpreoperativelivervolumetryincorporatingtheanatomicallocationofthecentralhepaticvein AT oezcelikarzu fullyautomatedpreoperativelivervolumetryincorporatingtheanatomicallocationofthecentralhepaticvein AT hoyerdieterp fullyautomatedpreoperativelivervolumetryincorporatingtheanatomicallocationofthecentralhepaticvein AT dayangacmurat fullyautomatedpreoperativelivervolumetryincorporatingtheanatomicallocationofthecentralhepaticvein AT hoschrene fullyautomatedpreoperativelivervolumetryincorporatingtheanatomicallocationofthecentralhepaticvein AT hauboldjohannes fullyautomatedpreoperativelivervolumetryincorporatingtheanatomicallocationofthecentralhepaticvein AT flaschelnils fullyautomatedpreoperativelivervolumetryincorporatingtheanatomicallocationofthecentralhepaticvein AT nensafelix fullyautomatedpreoperativelivervolumetryincorporatingtheanatomicallocationofthecentralhepaticvein AT malamutmanneugen fullyautomatedpreoperativelivervolumetryincorporatingtheanatomicallocationofthecentralhepaticvein |