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Increased Type I interferon signaling and brain endothelial barrier dysfunction in an experimental model of Alzheimer’s disease
Blood–brain barrier (BBB) dysfunction is emerging as a key pathogenic factor in the progression of Alzheimer’s disease (AD), where increased microvascular endothelial permeability has been proposed to play an important role. However, the molecular mechanisms leading to increased brain microvascular...
Autores principales: | Jana, Arundhati, Wang, Xinge, Leasure, Joseph W., Magana, Lissette, Wang, Li, Kim, Young-Mee, Dodiya, Hemraj, Toth, Peter T., Sisodia, Sangram S., Rehman, Jalees |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526723/ https://www.ncbi.nlm.nih.gov/pubmed/36182964 http://dx.doi.org/10.1038/s41598-022-20889-y |
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