GSDME deficiency leads to the aggravation of UVB-induced skin inflammation through enhancing recruitment and activation of neutrophils

Gasdermin E (GSDME)-mediated pyroptosis is induced in keratinocytes of UVB-challenged skin. The role of GSDME in UVB-caused skin damage remains unknown. To explore the role of GSDME in UVB-induced skin inflammation. We compared differences in skin appearance, histological features, keratinocyte deat...

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Detalles Bibliográficos
Autores principales: Chen, Yujie, Lian, Ni, Chen, Sihan, Xiao, Ta, Ke, Yangying, Zhang, Yiqun, Song, Changjun, Yang, Yong, Xu, Song, Gu, Heng, Chen, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526747/
https://www.ncbi.nlm.nih.gov/pubmed/36182937
http://dx.doi.org/10.1038/s41419-022-05276-9

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