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Inhibition of CCR8 attenuates Ang Ⅱ-induced vascular smooth muscle cell injury by suppressing the MAPK/NF-κB pathway

OBJECTIVE(S): Hyperinsulinemia, secondary to insulin resistance, may lead to vascular smooth muscle cell dysfunction. In the present research, we aimed to investigate the effect of Chemokine receptor 8 (CCR8) on angiotensin II (Ang II)-induced dysfunction of vascular smooth muscle cells (VSMCs) and...

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Detalles Bibliográficos
Autores principales: Liao, Lisi, Song, Di, Shi, Bobo, Chen, Ming, Wu, Linghu, Xu, Jinfeng, Dong, Fajin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526881/
https://www.ncbi.nlm.nih.gov/pubmed/36246058
http://dx.doi.org/10.22038/ijbms.2022.64524.14191