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Anti-asthmatic miR-224-5p inhibits the FHL1/MAPK pathway to repress airway smooth muscle cell proliferation in a murine model of asthma-like airway inflammation

BACKGROUND: The proliferation of airway smooth muscle cells (ASMCs) contributes to the contractility and inflammation in the pathophysiology of asthma. This intrigued us to clarify the effect of microRNA (miR)-224-5p on biological characteristics of ASMCs in mice with asthma-like airway inflammation...

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Detalles Bibliográficos
Autores principales:	Zhuang, Zhifang, Zhou, Yanjuan, Xu, Jiao, Pan, Leying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526920/ https://www.ncbi.nlm.nih.gov/pubmed/36184652 http://dx.doi.org/10.1186/s13223-022-00724-9

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