Safety assessment of compliant, highly invasive, lipid A-altered, O-antigen-defected Salmonella strains as prospective vaccine delivery systems

In the present study, two prospective Salmonella delivery strains, JOL2782 and JOL2837, were developed by gene deletions of lon and cpxR, which are related to cellular adhesion and intracellular survival. Additionally, sifA deletion was introduced for JOL2782, which confers immune susceptibility and...

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Detalles Bibliográficos
Autores principales: Aganja, Ram Prasad, Sivasankar, Chandran, Hewawaduge, Chamith, Lee, John Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526937/
https://www.ncbi.nlm.nih.gov/pubmed/36183131
http://dx.doi.org/10.1186/s13567-022-01096-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526937/
https://www.ncbi.nlm.nih.gov/pubmed/36183131
http://dx.doi.org/10.1186/s13567-022-01096-z

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