Targeting cancer stem cells with polymer nanoparticles for gastrointestinal cancer treatment

Nanomaterials are developing rapidly in the medical field, bringing new hope for treating various refractory diseases. Among them, polymer nanomaterials, with their excellent properties, have been used to treat various diseases, such as malignant tumors, diabetes, and nervous system diseases. Gastro...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Yao, Li, Bo, Cao, Qian, Liu, Tongjun, Li, Jiannan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526954/
https://www.ncbi.nlm.nih.gov/pubmed/36182897
http://dx.doi.org/10.1186/s13287-022-03180-9
_version_ 1784800984048861184
author Sun, Yao
Li, Bo
Cao, Qian
Liu, Tongjun
Li, Jiannan
author_facet Sun, Yao
Li, Bo
Cao, Qian
Liu, Tongjun
Li, Jiannan
author_sort Sun, Yao
collection PubMed
description Nanomaterials are developing rapidly in the medical field, bringing new hope for treating various refractory diseases. Among them, polymer nanomaterials, with their excellent properties, have been used to treat various diseases, such as malignant tumors, diabetes, and nervous system diseases. Gastrointestinal cancer is among the cancers with the highest morbidity and mortality worldwide. Cancer stem cells are believed to play an important role in the occurrence and development of tumors. This article summarizes the characteristics of gastrointestinal cancer stem cells and reviews the latest research progress in treating gastrointestinal malignant tumors using polymer nanoparticles to target cancer stem cells. In addition, the review article highlights the potential of polymer nanoparticles in targeting gastrointestinal cancer stem cells.
format Online
Article
Text
id pubmed-9526954
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-95269542022-10-03 Targeting cancer stem cells with polymer nanoparticles for gastrointestinal cancer treatment Sun, Yao Li, Bo Cao, Qian Liu, Tongjun Li, Jiannan Stem Cell Res Ther Review Nanomaterials are developing rapidly in the medical field, bringing new hope for treating various refractory diseases. Among them, polymer nanomaterials, with their excellent properties, have been used to treat various diseases, such as malignant tumors, diabetes, and nervous system diseases. Gastrointestinal cancer is among the cancers with the highest morbidity and mortality worldwide. Cancer stem cells are believed to play an important role in the occurrence and development of tumors. This article summarizes the characteristics of gastrointestinal cancer stem cells and reviews the latest research progress in treating gastrointestinal malignant tumors using polymer nanoparticles to target cancer stem cells. In addition, the review article highlights the potential of polymer nanoparticles in targeting gastrointestinal cancer stem cells. BioMed Central 2022-10-01 /pmc/articles/PMC9526954/ /pubmed/36182897 http://dx.doi.org/10.1186/s13287-022-03180-9 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Sun, Yao
Li, Bo
Cao, Qian
Liu, Tongjun
Li, Jiannan
Targeting cancer stem cells with polymer nanoparticles for gastrointestinal cancer treatment
title Targeting cancer stem cells with polymer nanoparticles for gastrointestinal cancer treatment
title_full Targeting cancer stem cells with polymer nanoparticles for gastrointestinal cancer treatment
title_fullStr Targeting cancer stem cells with polymer nanoparticles for gastrointestinal cancer treatment
title_full_unstemmed Targeting cancer stem cells with polymer nanoparticles for gastrointestinal cancer treatment
title_short Targeting cancer stem cells with polymer nanoparticles for gastrointestinal cancer treatment
title_sort targeting cancer stem cells with polymer nanoparticles for gastrointestinal cancer treatment
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526954/
https://www.ncbi.nlm.nih.gov/pubmed/36182897
http://dx.doi.org/10.1186/s13287-022-03180-9
work_keys_str_mv AT sunyao targetingcancerstemcellswithpolymernanoparticlesforgastrointestinalcancertreatment
AT libo targetingcancerstemcellswithpolymernanoparticlesforgastrointestinalcancertreatment
AT caoqian targetingcancerstemcellswithpolymernanoparticlesforgastrointestinalcancertreatment
AT liutongjun targetingcancerstemcellswithpolymernanoparticlesforgastrointestinalcancertreatment
AT lijiannan targetingcancerstemcellswithpolymernanoparticlesforgastrointestinalcancertreatment

Ejemplares similares