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Lucidenic acid A inhibits the binding of hACE2 receptor with spike protein to prevent SARS-CoV-2 invasion

High infection caused by mutations of SARS-CoV-2 calls for new prevention strategy. Ganoderma lucidum known as a superior immunoenhancer exhibits various antiviral effects, whether it can resist SARS-CoV-2 remains unclear. Herein, virtual screening combined with in vitro hACE2 inhibition assays were...

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Detalles Bibliográficos
Autores principales: Xu, Juan, Yang, WenTao, Pan, YiFeng, Xu, HaiShun, He, Liang, Zheng, BingSong, Xie, YingQiu, Wu, XueQian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526994/
https://www.ncbi.nlm.nih.gov/pubmed/36179993
http://dx.doi.org/10.1016/j.fct.2022.113438

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