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JACKIE: Fast Enumeration of Genome-Wide Single- and Multicopy CRISPR Target Sites and Their Off-Target Numbers

Zinc finger protein-, transcription activator like effector-, and CRISPR-based methods for genome and epigenome editing and imaging have provided powerful tools to investigate functions of genomes. Targeting sequence design is vital to the success of these experiments. Although existing design softw...

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Detalles Bibliográficos
Autores principales: Zhu, Jacqueline Jufen, Cheng, Albert Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527058/
https://www.ncbi.nlm.nih.gov/pubmed/35830604
http://dx.doi.org/10.1089/crispr.2022.0042