COVID-19 vaccination may enhance hippocampal neurogenesis in adults

Emerging evidence suggests a detrimental impact of COVID-19 illness on the continued hippocampal neurogenesis in adults. In contrast, the existing literature supports an enhancing effect of COVID-19 vaccination on adult hippocampal neurogenesis. Vaccines against respiratory infections, including inf...

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Detalles Bibliográficos
Autores principales: Kumar, Ashutosh, Narayan, Ravi K., Prasoon, Pranav, Jha, Rakesh K., Kumar, Sujeet, Kumari, Chiman, Pandey, Sada N., Faiq, Muneeb A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2023
Materias:
Viewpoint
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527215/
https://www.ncbi.nlm.nih.gov/pubmed/36202167
http://dx.doi.org/10.1016/j.bbi.2022.09.020
Descripción
Sumario:Emerging evidence suggests a detrimental impact of COVID-19 illness on the continued hippocampal neurogenesis in adults. In contrast, the existing literature supports an enhancing effect of COVID-19 vaccination on adult hippocampal neurogenesis. Vaccines against respiratory infections, including influenza, have been shown to enhance hippocampal neurogenesis in adult-age animals. We propose that a similar benefit may happen in COVID-19 vaccinated adults. The vaccine-induced enhancement of the hippocampal neurogenesis in adults thus may protect against age-related cognitive decline and mental disorders. It also hints at an added mental health benefit of the COVID-19 vaccination programs in adults.

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