COVID-19 vaccination may enhance hippocampal neurogenesis in adults

Emerging evidence suggests a detrimental impact of COVID-19 illness on the continued hippocampal neurogenesis in adults. In contrast, the existing literature supports an enhancing effect of COVID-19 vaccination on adult hippocampal neurogenesis. Vaccines against respiratory infections, including inf...

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Autores principales: Kumar, Ashutosh, Narayan, Ravi K., Prasoon, Pranav, Jha, Rakesh K., Kumar, Sujeet, Kumari, Chiman, Pandey, Sada N., Faiq, Muneeb A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2023
Materias:
Viewpoint
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527215/
https://www.ncbi.nlm.nih.gov/pubmed/36202167
http://dx.doi.org/10.1016/j.bbi.2022.09.020
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author Kumar, Ashutosh
Narayan, Ravi K.
Prasoon, Pranav
Jha, Rakesh K.
Kumar, Sujeet
Kumari, Chiman
Pandey, Sada N.
Faiq, Muneeb A.
author_facet Kumar, Ashutosh
Narayan, Ravi K.
Prasoon, Pranav
Jha, Rakesh K.
Kumar, Sujeet
Kumari, Chiman
Pandey, Sada N.
Faiq, Muneeb A.
author_sort Kumar, Ashutosh
collection PubMed
description Emerging evidence suggests a detrimental impact of COVID-19 illness on the continued hippocampal neurogenesis in adults. In contrast, the existing literature supports an enhancing effect of COVID-19 vaccination on adult hippocampal neurogenesis. Vaccines against respiratory infections, including influenza, have been shown to enhance hippocampal neurogenesis in adult-age animals. We propose that a similar benefit may happen in COVID-19 vaccinated adults. The vaccine-induced enhancement of the hippocampal neurogenesis in adults thus may protect against age-related cognitive decline and mental disorders. It also hints at an added mental health benefit of the COVID-19 vaccination programs in adults.
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spelling pubmed-95272152022-10-03 COVID-19 vaccination may enhance hippocampal neurogenesis in adults Kumar, Ashutosh Narayan, Ravi K. Prasoon, Pranav Jha, Rakesh K. Kumar, Sujeet Kumari, Chiman Pandey, Sada N. Faiq, Muneeb A. Brain Behav Immun Viewpoint Emerging evidence suggests a detrimental impact of COVID-19 illness on the continued hippocampal neurogenesis in adults. In contrast, the existing literature supports an enhancing effect of COVID-19 vaccination on adult hippocampal neurogenesis. Vaccines against respiratory infections, including influenza, have been shown to enhance hippocampal neurogenesis in adult-age animals. We propose that a similar benefit may happen in COVID-19 vaccinated adults. The vaccine-induced enhancement of the hippocampal neurogenesis in adults thus may protect against age-related cognitive decline and mental disorders. It also hints at an added mental health benefit of the COVID-19 vaccination programs in adults. Elsevier Inc. 2023-01 2022-10-03 /pmc/articles/PMC9527215/ /pubmed/36202167 http://dx.doi.org/10.1016/j.bbi.2022.09.020 Text en © 2022 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Viewpoint
Kumar, Ashutosh
Narayan, Ravi K.
Prasoon, Pranav
Jha, Rakesh K.
Kumar, Sujeet
Kumari, Chiman
Pandey, Sada N.
Faiq, Muneeb A.
COVID-19 vaccination may enhance hippocampal neurogenesis in adults
title COVID-19 vaccination may enhance hippocampal neurogenesis in adults
title_full COVID-19 vaccination may enhance hippocampal neurogenesis in adults
title_fullStr COVID-19 vaccination may enhance hippocampal neurogenesis in adults
title_full_unstemmed COVID-19 vaccination may enhance hippocampal neurogenesis in adults
title_short COVID-19 vaccination may enhance hippocampal neurogenesis in adults
title_sort covid-19 vaccination may enhance hippocampal neurogenesis in adults
topic Viewpoint
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527215/
https://www.ncbi.nlm.nih.gov/pubmed/36202167
http://dx.doi.org/10.1016/j.bbi.2022.09.020
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