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Extrachromosomal circular DNA: biogenesis, structure, functions and diseases

Extrachromosomal circular DNA (eccDNA), ranging in size from tens to millions of base pairs, is independent of conventional chromosomes. Recently, eccDNAs have been considered an unanticipated major source of somatic rearrangements, contributing to genomic remodeling through chimeric circularization...

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Detalles Bibliográficos
Autores principales:	Yang, Ludi, Jia, Ruobing, Ge, Tongxin, Ge, Shengfang, Zhuang, Ai, Chai, Peiwei, Fan, Xianqun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527254/ https://www.ncbi.nlm.nih.gov/pubmed/36184613 http://dx.doi.org/10.1038/s41392-022-01176-8

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