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Luteolin enhances erlotinib’s cell proliferation inhibitory and apoptotic effects in glioblastoma cell lines

The epidermal growth factor (EGFR) receptor is frequently overexpressed in glioblastoma multiforme IV (GBM). Increased expression of EGFR leads to increased proliferation, decreased apoptosis, and increased resistance to chemotherapeutic agents. A small molecule called erlotinib inhibits EGFR recept...

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Detalles Bibliográficos
Autores principales:	Powe, Erika, Parschauer, Daniel, Istifan, Jessica, Lin, Stacy, Duan, Huanyun, Gryka, Rebecca, Jean-Louis, Denise, Tiwari, Amit K., Amos, Samson
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527275/ https://www.ncbi.nlm.nih.gov/pubmed/36199696 http://dx.doi.org/10.3389/fphar.2022.952169

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