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XMU-MP-1 attenuates osteoarthritis via inhibiting cartilage degradation and chondrocyte apoptosis

Osteoarthritis (OA) is the most prevalent type of degenerative joint disease; it is reported to be associated with inflammatory responses, chondrocyte apoptosis, and cartilage degeneration. XMU-MP-1 is a selective MST1/2 inhibitor which activates the downstream effector YAP and promotes cell growth....

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Detalles Bibliográficos
Autores principales:	Hao, Xue, Zhao, Jing, Jia, Liyuan, He, Ting, Wang, Huanbo, Fan, Jing, Yang, Yating, Su, Fei, Lu, Qingda, Zheng, Chao, Yang, Liu, Jie, Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527278/ https://www.ncbi.nlm.nih.gov/pubmed/36199358 http://dx.doi.org/10.3389/fbioe.2022.998077

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